User profiles for S. Jernigan
Stephen JerniganAssistant Professor, University of Kansas Medical Center Verified email at kumc.edu Cited by 977 |
[HTML][HTML] Mechanisms of DNA damage, DNA hypomethylation, and tumor progression in the folate/methyl-deficient rat model of hepatocarcinogenesis
…, M Pogribna, BJ Miller, S Jernigan, S Melnyk - The Journal of …, 2003 - Elsevier
Using the folate/methyl-deficient rat model of hepatocarcinogenesis, we obtained evidence
that may provide new insights into a major unresolved paradox in DNA methylation and …
that may provide new insights into a major unresolved paradox in DNA methylation and …
[HTML][HTML] Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism
SJ James, P Cutler, S Melnyk, S Jernigan… - The American journal of …, 2004 - Elsevier
Background Autism is a complex neurodevelopmental disorder that usually presents in
early childhood and that is thought to be influenced by genetic and environmental factors. …
early childhood and that is thought to be influenced by genetic and environmental factors. …
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism
SJ James, S Melnyk, S Jernigan… - American Journal of …, 2006 - Wiley Online Library
Autism is a behaviorally defined neurodevelopmental disorder usually diagnosed in early
childhood that is characterized by impairment in reciprocal communication and speech, …
childhood that is characterized by impairment in reciprocal communication and speech, …
Resveratrol acts as a mixed agonist/antagonist for estrogen receptors α and β
JL Bowers, VV Tyulmenkov, SC Jernigan… - …, 2000 - academic.oup.com
… This indicates that those tissues that uniquely express ERβ or that express higher levels of
ERβ than ERα may be more sensitive to resveratrol’s estrogen agonist activity. For the natural…
ERβ than ERα may be more sensitive to resveratrol’s estrogen agonist activity. For the natural…
The effect of exercise on neuropathic symptoms, nerve function, and cutaneous innervation in people with diabetic peripheral neuropathy
PM Kluding, M Pasnoor, R Singh, S Jernigan… - Journal of Diabetes and …, 2012 - Elsevier
Although exercise can significantly reduce the prevalence and severity of diabetic
complications, no studies have evaluated the impact of exercise on nerve function in people with …
complications, no studies have evaluated the impact of exercise on nerve function in people with …
Guidelines for prehospital management of traumatic brain injury 2nd edition
…, HMA Hennes, AS Jagoda, S Jernigan… - Prehospital …, 2008 - Taylor & Francis
Worldwide, traumatic brain injury (TBI) is a leading cause of death and permanent disability.
In the United States, there are approximately 1.4 million reported cases of TBI each year. …
In the United States, there are approximately 1.4 million reported cases of TBI each year. …
[HTML][HTML] Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism
Research into the metabolic phenotype of autism has been relatively unexplored despite
the fact that metabolic abnormalities have been implicated in the pathophysiology of several …
the fact that metabolic abnormalities have been implicated in the pathophysiology of several …
[HTML][HTML] Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism
…, S Melnyk, G Fuchs, T Reid, S Jernigan… - The American journal of …, 2009 - Elsevier
… after intervention were determined using the paired Student’s t test with significance set at
0.05. Comparisons between case and control children were done using the Student’s t test. …
0.05. Comparisons between case and control children were done using the Student’s t test. …
Uteroplacental insufficiency alters DNA methylation, one-carbon metabolism, and histone acetylation in IUGR rats
…, S Melnyk, A Piroozi, S Jernigan… - Physiological …, 2004 - journals.physiology.org
Uteroplacental insufficiency leads to intrauterine growth retardation (IUGR) and increases
the risk of insulin resistance and hypertriglyceridemia in both humans and rats. Postnatal …
the risk of insulin resistance and hypertriglyceridemia in both humans and rats. Postnatal …
[HTML][HTML] Estrogen response element-dependent regulation of transcriptional activation of estrogen receptors α and β by coactivators and corepressors
CM Klinge, SC Jernigan, KA Mattingly… - Journal of …, 2004 - jme.bioscientifica.com
… One possible explanation of these results is that GRIP1 requires a cellular cofactor(s) for
the other EREs that is not expressed in CHO-K1 cells. However, GRIP1 did not enhance E 2 -…
the other EREs that is not expressed in CHO-K1 cells. However, GRIP1 did not enhance E 2 -…