[PDF][PDF] Neue Entwicklungen in der Demenzdiagnostik
GW Eschweiler, T Leyhe, S Klöppel, M Hüll - Deutsches Ärzteblatt, 2010 - researchgate.net
… Conclusion: The early, preclinical phase of Alzheimer’s disease involves what has been …
’s disease correctly in this phase can be raised above 80%. Early detection of Alzheimer’s …
’s disease correctly in this phase can be raised above 80%. Early detection of Alzheimer’s …
CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion
…, EY Kim, M Kimble, P King, ML Klimek, S Klöppel… - Neurology, 2012 - AAN Enterprises
Objective: Age at onset of diagnostic motor manifestations in Huntington disease (HD) is
strongly correlated with an expanded CAG trinucleotide repeat. The length of the normal CAG …
strongly correlated with an expanded CAG trinucleotide repeat. The length of the normal CAG …
Automatic classification of MR scans in Alzheimer's disease
S Klöppel, CM Stonnington, C Chu, B Draganski… - Brain, 2008 - academic.oup.com
To be diagnostically useful, structural MRI must reliably distinguish Alzheimer's disease (AD)
from normal aging in individual scans. Recent advances in statistical learning theory have …
from normal aging in individual scans. Recent advances in statistical learning theory have …
Estimating the age of healthy subjects from T1-weighted MRI scans using kernel methods: exploring the influence of various parameters
The early identification of brain anatomy deviating from the normal pattern of growth and
atrophy, such as in Alzheimer's disease (AD), has the potential to improve clinical outcomes …
atrophy, such as in Alzheimer's disease (AD), has the potential to improve clinical outcomes …
Consensus paper: combining transcranial stimulation with neuroimaging
…, L De Gennaro, AP Strafella, S Kähkönen, S Klöppel… - Brain stimulation, 2009 - Elsevier
In the last decade, combined transcranial magnetic stimulation (TMS)-neuroimaging studies
have greatly stimulated research in the field of TMS and neuroimaging. Here, we review …
have greatly stimulated research in the field of TMS and neuroimaging. Here, we review …
Evidence for segregated and integrative connectivity patterns in the human basal ganglia
… PICo involves repeated iterations of a streamline process using Monte Carlo methods to
model inherent uncertainty in the orientation of the principal diffusion direction(s) defined for …
model inherent uncertainty in the orientation of the principal diffusion direction(s) defined for …
Implementation of subjective cognitive decline criteria in research studies
… future, change in SCD may be one way of assessing longitudinal functional benefit in
secondary prevention trials [5], but there will need to a consensus on which particular measure(s) …
secondary prevention trials [5], but there will need to a consensus on which particular measure(s) …
[HTML][HTML] BrainAGE in Mild Cognitive Impaired Patients: Predicting the Conversion to Alzheimer's Disease
Alzheimer’s disease (AD), the most common form of dementia, shares many aspects of
abnormal brain aging. We present a novel magnetic resonance imaging (MRI)-based biomarker …
abnormal brain aging. We present a novel magnetic resonance imaging (MRI)-based biomarker …
Accuracy of dementia diagnosis—a direct comparison between radiologists and a computerized method
… The SVM results are taken from our previously reported study for comparison (Kloppel et al.,
… 20 subjects are included from each diagnostic group (Kloppel et al., 2008a) but the number …
… 20 subjects are included from each diagnostic group (Kloppel et al., 2008a) but the number …
Combining functional and anatomical connectivity reveals brain networks for auditory language comprehension
…, H Küpper, P Kellmeyer, D Kümmerer, S Klöppel… - Neuroimage, 2010 - Elsevier
… However, in the case of fMRI with sampling rates of about 2 s, interactions must be regarded
as instantaneous, thus information of the past cannot be used to explain the direction of …
as instantaneous, thus information of the past cannot be used to explain the direction of …