Validating the sensitivity of inhomogeneous magnetization transfer (ihMT) MRI to myelin with fluorescence microscopy
Inhomogeneous Magnetization Transfer (ihMT) is a development from the MT MRI technique.
IhMT can be considered as a dipolar order relaxation time (T 1D ) weighted imaging …
IhMT can be considered as a dipolar order relaxation time (T 1D ) weighted imaging …
Whole brain inhomogeneous magnetization transfer (ihMT) imaging: sensitivity enhancement within a steady‐state gradient echo sequence
S Mchinda, G Varma, VH Prevost… - Magnetic resonance …, 2018 - Wiley Online Library
… This elementary sequence kernel (RF burst + readout) is repeated until a steady state is
reached and may be repeated as long as necessary to acquire a whole 3D volume, as for …
reached and may be repeated as long as necessary to acquire a whole 3D volume, as for …
Evaluation of the sensitivity of inhomogeneous magnetization transfer (ihMT) MRI for multiple sclerosis
E Van Obberghen, S Mchinda… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Inhomogeneous magnetization transfer is a new endogenous
MR imaging contrast mechanism that has demonstrated high specificity for myelin. Here, …
MR imaging contrast mechanism that has demonstrated high specificity for myelin. Here, …
Optimization of inhomogeneous magnetization transfer (ihMT) MRI contrast for preclinical studies using dipolar relaxation time (T1D) filtering
VH Prevost, OM Girard, S Mchinda, G Varma… - NMR in …, 2017 - Wiley Online Library
A pulsed inhomogeneous magnetization transfer (ihMT)‐prepared fast imaging sequence
was implemented at 11.75 T for preclinical studies on mouse central nervous system. A …
was implemented at 11.75 T for preclinical studies on mouse central nervous system. A …
Low duty-cycle pulsed irradiation reduces magnetization transfer and increases the inhomogeneous magnetization transfer effect
G Varma, OM Girard, S Mchinda, VH Prevost… - Journal of Magnetic …, 2018 - Elsevier
Intense off-resonant RF irradiation can lead to saturation of the macromolecular pool
magnetization and enhance bound pool dipolar order responsible for the inhomogeneous …
magnetization and enhance bound pool dipolar order responsible for the inhomogeneous …
MRI assessment of multiple dipolar relaxation time (T1D) components in biological tissues interpreted with a generalized inhomogeneous magnetization transfer …
VND Carvalho, A Hertanu, A Grélard, S Mchinda… - Journal of Magnetic …, 2020 - Elsevier
T 1 D , the relaxation time of dipolar order, is sensitive to slow motional processes. Thus T 1
D is a probe for membrane dynamics and organization that could be used to characterize …
D is a probe for membrane dynamics and organization that could be used to characterize …
Contribution of the MP2RAGE 7T sequence in MS lesions of the cervical spinal cord
…, N Fabiani, S Demortière, S Mchinda… - American Journal …, 2023 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The detection of spinal cord lesions in patients with MS is
challenging. Recently, the 3D MP2RAGE sequence demonstrated its usefulness at 3T. …
challenging. Recently, the 3D MP2RAGE sequence demonstrated its usefulness at 3T. …
A strategy to reduce the sensitivity of inhomogeneous magnetization transfer (ihMT) imaging to radiofrequency transmit field variations at 3 T
… Although the complete description of these effects is outside the scope of the present paper,
more information is provided in the Discussion section and Supporting Information, which is …
more information is provided in the Discussion section and Supporting Information, which is …
Anisotropy of inhomogeneous magnetization transfer (ihMT) in white matter
OM Girard, VH Prevost, S Mchinda, G Varma… - Proc. Intl. Soc. Mag …, 2017 - hal.science
Inhomogeneous magnetization transfer (ihMT) is a new endogenous contrast mechanism that
has been proposed for imaging myelinated tissues. The dipolar interaction underlying the …
has been proposed for imaging myelinated tissues. The dipolar interaction underlying the …
Validation of inhomogeneous magnetization transfer (ihMT) as a myelin biomarker
The ihMT (inhomogeneous Magnetization transfer) signal qualitatively demonstrates sensitivity
for myelinated structures. However, image intensity and contrast vary with the saturation …
for myelinated structures. However, image intensity and contrast vary with the saturation …