Association of MTOR mutations with developmental brain disorders, including megalencephaly, focal cortical dysplasia, and pigmentary mosaicism

…, EA Boyle, S Collins, G Ishak, SL Poliachik… - JAMA …, 2016 - jamanetwork.com
Importance Focal cortical dysplasia (FCD), hemimegalencephaly, and megalencephaly
constitute a spectrum of malformations of cortical development with shared neuropathologic …

[PDF][PDF] The effect of muscle dysfunction on bone mass and morphology

TS Gross, SL Poliachik, J Prasad, SD Bain - J Musculoskelet Neuronal …, 2010 - ismni.org
… Of relevance to this discussion, Borelli’s observation emphasizes … perspective, this concept
formed the basis for Roux’s … strongly underlie the coupling of an individual’s muscle strength …

Enabling bone formation in the aged skeleton via rest-inserted mechanical loading

…, SC Agans, KA King, NY Moy, SL Poliachik… - Bone, 2003 - Elsevier
The mild and moderate physical activity most successfully implemented in the elderly has
proven ineffective in augmenting bone mass. We have recently reported that inserting 10 s of …

MRI-informed muscle biopsies correlate MRI with pathology and DUX4 target gene expression in FSHD

…, CJ Wong, CB Budech, SL Poliachik… - Human Molecular …, 2019 - academic.oup.com
… Histologic muscle samples were processed and scored in Dr Tawil’s lab, RNA extraction for
sequencing was performed in Dr Tapscott’s lab and all MRI interpretation and scoring were …

Why rest stimulates bone formation: a hypothesis based on complex adaptive phenomenon

TS Gross, SL Poliachik, BJ Ausk… - Exercise and sport …, 2004 - journals.lww.com
… Based on our initial observations regarding 10 s of rest, the relative benefits of 3, 7, and 14
s … Although 3 and 7 s did not alter bone adaptation compared with cyclic loading, 14 s of rest …

Rest-inserted loading rapidly amplifies the response of bone to small increases in strain and load cycles

S Srinivasan, BJ Ausk, SL Poliachik… - Journal of applied …, 2007 - journals.physiology.org
We hypothesized that a 10-s rest interval (at zero load) inserted between each load cycle
would increase the osteogenic effects of mechanical loading near previously identified …

Transient muscle paralysis disrupts bone homeostasis by rapid degradation of bone morphology

SL Poliachik, SD Bain, DW Threet, P Huber, TS Gross - Bone, 2010 - Elsevier
We have previously shown that transient paralysis of murine hindlimb muscles causes profound
degradation of both trabecular and cortical bone in the adjacent skeleton within 3 weeks…

Thresholds for inertial cavitation in albunex suspensions under pulsed ultrasound conditions

…, WS Chen, PD Mourad, SL Poliachik… - IEEE transactions on …, 2001 - ieeexplore.ieee.org
… In this section, we present t,lie experirncntel result,s for P1, the thrcshold for inertial cavitation
associated with the disappearance of echo enhancement, arid P2, the threshold for the …

Skeletal muscle edema in muscular dystrophy: clinical and diagnostic implications

SL Poliachik, SD Friedman, GT Carter… - Physical Medicine …, 2012 - pmr.theclinics.com
Numerous major forms of muscular dystrophy have been identified. 1 The type of muscular
dystrophy influences the progression of muscle degradation and the pattern of muscle …

Effect of high-intensity focused ultrasound on whole blood with and without microbubble contrast agent

SL Poliachik, WL Chandler, PD Mourad… - Ultrasound in medicine …, 1999 - Elsevier
… durations of 10 ms to 1 s at spatial average intensities of 560 … 2360 W/cm 2 for 1 s resulted
in measurable cavitation and a … per mL whole blood exposed for 1 s, a threshold was seen at …