Multiplicity of mammalian reductases for xenobiotic carbonyl compounds

T Matsunaga, S Shintani, A Hara - Drug metabolism and …, 2006 - jstage.jst.go.jp
… SDR and AKR superfamilies (Table 4), and AKR1C2 may be the major enzyme in the reductive
metabolism of ketotifen because of its extremely high reactivity towards both the R- and S

Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial

…, H Matsubara, T Murohara, U Ikeda, S Shintani… - The Lancet, 2002 - thelancet.com
Background Preclinical studies have established that implantation of bone marrow-mononuclear
cells, including endothelial progenitor cells, into ischaemic limbs increases collateral …

Mobilization of endothelial progenitor cells in patients with acute myocardial infarction

S Shintani, T Murohara, H Ikeda, T Ueno, T Honma… - Circulation, 2001 - Am Heart Assoc
… Data were subjected to 1-way ANOVA followed by Fisher’s test for comparison between any
… The precise origin(s) of circulating VEGF is unknown, but ischemic cardiac tissues likely …

Implantation of bone marrow mononuclear cells into ischemic myocardium enhances collateral perfusion and regional function via side supply of angioblasts …

…, Y Mori, O Iba, E Tateishi, A Kosaki, S Shintani… - Circulation, 2001 - Am Heart Assoc
… Statistical analyses were performed with a 1-way ANOVA followed by pairwise contrasts
with Dunnett’s test. Data (meanąSEM) were considered statistically significant at a value of P<…

[HTML][HTML] Cardiac thin filament regulation and the Frank–Starling mechanism

…, SA Shintani, K Oyama, T Terui, S Minamisawa… - The journal of …, 2014 - Springer
… While PKA acts under physiologic conditions to control the heart’s inotropic and chronotropic
states, various PKC isoforms are activated in diseased states [eg, 14]. Both PKA and PKC …

[HTML][HTML] Transplanted cord blood–derived endothelial precursor cells augment postnatal neovascularization

T Murohara, H Ikeda, J Duan, S Shintani… - The Journal of …, 2000 - Am Soc Clin Investig
… These mAb’s were all mouse IgG 1 , and thus negative control … Aliquots of cells were then
stained with primary mAb’s directed to … All mAb’s recognize the extracellular domain of each …

Basic evidence of molecular targeted therapy for oral cancer and salivary gland cancer

H Hamakawa, K Nakashiro, T Sumida, S Shintani… - Head & …, 2008 - Wiley Online Library
… inhibit the proliferation of OSCC cell lines in a dose‐ and time‐dependent manner and lead
to cell cycle arrest with accumulation of cells in the G1 phase, and a decrease of cells in S

Augmentation of postnatal neovascularization with autologous bone marrow transplantation

S Shintani, T Murohara, H Ikeda, T Ueno, K Sasaki… - Circulation, 2001 - Am Heart Assoc
Background—Endothelial progenitor cells (EPCs) have been identified in adult human
peripheral blood. Because circulating EPCs should originate from bone marrow (BM), we …

[HTML][HTML] Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction

S Weis, S Shintani, A Weber… - The Journal of …, 2004 - Am Soc Clin Investig
Ischemia resulting from myocardial infarction (MI) promotes VEGF expression, leading to
vascular permeability (VP) and edema, a process that we show here contributes to tissue injury …

Dentin matrix protein 1 is predominantly expressed in chicken and rat osteocytes but not in osteoblasts

S Toyosawa, S Shintani, T Fujiwara… - Journal of Bone and …, 2001 - academic.oup.com
Although osteocytes are the most abundant cells in bone, little is known about their function,
and no specific marker protein for osteocytes has been described. Dentin matrix protein 1 (…