User profiles for S.N. Jespersen

Sune Nørhøj Jespersen

Professor, CFIN/MINDLab and Department of Physics, Aarhus University, Denmark
Verified email at cfin.au.dk
Cited by 7765

Quantifying brain microstructure with diffusion MRI: Theory and parameter estimation

DS Novikov, E Fieremans, SN Jespersen… - NMR in …, 2019 - Wiley Online Library
We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …

On modeling

…, VG Kiselev, SN Jespersen - Magnetic resonance in …, 2018 - Wiley Online Library
Mapping tissue microstructure with MRI holds great promise as a noninvasive window into
tissue organization at the cellular level. Having originated within the realm of diffusion NMR in …

Conventions and nomenclature for double diffusion encoding NMR and MRI

N Shemesh, SN Jespersen… - Magnetic resonance …, 2016 - Wiley Online Library
Stejskal and Tanner's ingenious pulsed field gradient design from 1965 has made diffusion
NMR and MRI the mainstay of most studies seeking to resolve microstructural information in …

The roles of cerebral blood flow, capillary transit time heterogeneity, and oxygen tension in brain oxygenation and metabolism

SN Jespersen, L Østergaard - Journal of cerebral blood flow …, 2012 - journals.sagepub.com
Normal brain function depends critically on moment-to-moment regulation of oxygen supply
by the bloodstream to meet changing metabolic needs. Neurovascular coupling, a range of …

Modeling dendrite density from magnetic resonance diffusion measurements

SN Jespersen, CD Kroenke, L Østergaard… - Neuroimage, 2007 - Elsevier
Diffusion-weighted imaging (DWI) provides a noninvasive tool to probe tissue microstructure.
We propose a simplified model of neural cytoarchitecture intended to capture the essential …

Neurite density from magnetic resonance diffusion measurements at ultrahigh field: comparison with light microscopy and electron microscopy

SN Jespersen, CR Bjarkam, JR Nyengaard… - Neuroimage, 2010 - Elsevier
Due to its unique sensitivity to tissue microstructure, diffusion-weighted magnetic resonance
imaging (MRI) has found many applications in clinical and fundamental science. With few …

Orientationally invariant metrics of apparent compartment eccentricity from double pulsed field gradient diffusion experiments

SN Jespersen, H Lundell, CK Sønderby… - NMR in …, 2013 - Wiley Online Library
Jespersen 22 showed that, for macroscopically isotropic samples in the long diffusion
time limit, ε is proportional to the measure of eccentricity I MA introduced in 21: I MA = (15/2)ε. …

The capillary dysfunction hypothesis of Alzheimer's disease

…, H Brændgaard, K Mouridsen, SN Jespersen… - Neurobiology of …, 2013 - Elsevier
It is widely accepted that hypoperfusion and changes in capillary morphology are involved
in the etiopathogenesis of Alzheimer's disease (AD). This is difficult to reconcile with the …

Determination of axonal and dendritic orientation distributions within the developing cerebral cortex by diffusion tensor imaging

SN Jespersen, LA Leigland, A Cornea… - IEEE transactions on …, 2011 - ieeexplore.ieee.org
… *SN Jespersen is with the Center of Functionally Integrative Neuroscience, Aarhus University
Hospital, Aarhus, Denmark (phone: +45 89493334; fax: +45 89494400; e-mail: sune@cfin.…

Capillary transit time heterogeneity and flow-metabolism coupling after traumatic brain injury

…, B Hansen, SN Jespersen… - Journal of Cerebral …, 2014 - journals.sagepub.com
Most patients who die after traumatic brain injury (TBI) show evidence of ischemic brain
damage. Nevertheless, it has proven difficult to demonstrate cerebral ischemia in TBI patients. …