… Using exploratory graphics, none of the studies were outliers; however, the Luijten et al.
study (MR CLEAN) stood out in influence analysis, which was evident again in the bivariate box …

Importance Dual thrombolytic treatment with small bolus alteplase and mutant prourokinase
has the potential to be a safer and more efficacious treatment for ischemic stroke than …

Background Machine learning algorithms hold the potential to contribute to fast and accurate
detection of large vessel occlusion (LVO) in patients with suspected acute ischemic stroke. …

Background Intracranial hemorrhage (ICH) is a frequent complication after endovascular
stroke treatment. Objective To assess the association of the occurrence and type of ICH after …

Restoring blood flow to brain tissue at risk of infarction is essential for tissue survival and
clinical outcome. We used cerebral blood flow (CBF) quantified with multiple post-labeling …

Objective To investigate the association between white matter lesions (WML) and functional
outcome in patients with acute ischemic stroke (AIS) and the modification of the effect of …

Background Brain atrophy is suggested to impair the potential for functional recovery after
acute ischemic stroke. We assessed whether the effect of endovascular treatment is modified …

Background The effectiveness of alteplase for ischemic stroke treatment is limited, partly
due to the occurrence of intracranial and extracranial hemorrhage. Mutant pro-urokinase (m-…

… Author links open overlay panel Sven PR Luijten a , Sophie C. van der Donk a , Kars CJ
Compagne a , Lonneke SF Yo b , Marieke ES Sprengers c , Charles BLM Majoie c , Yvo BWEM …

Background and Objectives In patients with ischemic stroke undergoing endovascular
treatment (EVT), time to treatment and collateral status are important prognostic factors and may …