Background— Angiogenesis is a critical feature of plaque development in atherosclerosis
and might play a key role in both the initiation and later rupture of plaques that lead to …

Nanotechnology-based tools and techniques are rapidly emerging in the fields of medical
imaging and targeted drug delivery. Employing constructs such as dendrimers, liposomes, …

Early noninvasive detection and characterization of solid tumors and their supporting
neovasculature is a fundamental prerequisite for effective therapeutic intervention, particularly …

Objective— Angiogenic expansion of the vasa vasorum is a well-known feature of progressive
atherosclerosis, suggesting that antiangiogenic therapies may stabilize or regress plaques…

… onto a conventional 1H image of the site (D) reveals PFOB and CE labeled cells localized
to … Lanza, who are cofounders and equity holders in Kereos, Inc., and Shelton D. Caruthers, …

Before molecular imaging with MRI can be applied clinically, certain problems, such as the
potential sparseness of molecular epitopes on targeted cell surfaces, and the relative …

Background— Valvular pathology can be analyzed quickly and accurately through the use
of Doppler ultrasound. For aortic stenosis, the continuity equation approach with Doppler …

Neovascularization is a critical component in the progression of malignant melanoma. The
objective of this study was to determine whether α ν β 3 ‐targeted paramagnetic …

Context While gray matter T2 hypointensity in multiple sclerosis (MS) has been associated
with physical disability and clinical course, previous studies have relied on visual magnetic …

Advances in bionanotechnology are poised to impact the field of cardiovascular diagnosis
and therapy for decades to come. This review seeks to illustrate selected examples of newly …