Background and Purpose Occluding a large intracranial artery in rats produces a brain lesion
that grows in terms of an increase in both surface area and number of necrotic neurons. …

Integrin α1β1 is a collagen receptor abundantly expressed on microvascular endothelial
cells. As well as being the only collagen receptor able to activate the Ras/Shc/mitogen-activated …

Background and Purpose— The goal of this study was to determine the temporal profile of
several matrix metalloproteinases (MMPs), tissue inhibitors of MMPs (TIMPs), and laminin (an …

Object. The goal of this study was to determine the frequency of hemicraniectomy-associated
lesions and their potential effect on the risk of mortality in patients suffering from malignant …

Reperfusion injury is a complication of recanalization therapies after focal cerebral ischemia.
The disruption of the blood–brain barrier (BBB) caused by up-regulated metalloproteinases …

Introduction The objective of this prospective study was to assess short- and long-term efficacy
of exercise training (ET) as add-on to medical therapy in patients with connective tissue …

Background and Purpose Integrins participate in cerebral microvascular integrity and signaling
during focal ischemia/reperfusion. The integrin subunits α 1 , α 6 , and β 1 are distributed …

The integrity of cerebral microvessels requires the close apposition of the endothelium to
the astrocyte endfeet. Integrins α 1 β 1 and α 6 β 4 are cellular matrix receptors that may …

Background: Deposition of amyloid β in senile plaques and in cerebral blood vessels is one
hallmark of the pathogenesis of Alzheimer's disease (AD). The ability of several matrix …

Diphenyleneiodonium (DPI) is an inhibitor of the free radical producing NAD(P)H-oxidase.
We tested whether DPI shows neuroprotective properties after focal cerebral ischemia and we …