… The subjects, both of whose 2 alleles of SNP 276 are the G (G/G genotype), had an
approximately doubled risk for developing type 2 diabetes as compared with those with the T/T …

… adiponectin levels than those with the T/T genotype. Subjects with the G/G genotype at
position 276 had a higher insulin resistance index than those with T/T. Importantly, subjects with …

… Moreover, T-cadherin by itself was thought to have no effect on adiponectin cellular … ,
because T-cadherin is without an intracellular domain. These data raised the possibility that T-…

… Yamauchi, T. et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by
activating … Yamauchi, T. et al. Globular adiponectin protected ob/ob mice from diabetes and apoE …

Adiponectin is an adipocyte-derived hormone. Recent genome-wide scans have mapped a
susceptibility locus for type 2 diabetes and metabolic syndrome to chromosome 3q27, where …

Current genome-wide association studies do not yet capture sufficient diversity in
populations and scope of phenotypes. To expand an atlas of genetic associations in non-European …

Adiponectin plays a central role as an antidiabetic and antiatherogenic adipokine. AdipoR1
and AdipoR2 serve as receptors for adiponectin in vitro, and their reduction in obesity seems …

… -tailed t-tests. Data involving more than two groups were assessed by analysis of variance
(ANOVA). … We thank BM Spiegelman for critical discussions and reading of the manuscript; T. …

Adiponectin (Ad) is a hormone secreted by adipocytes that regulates energy homeostasis
and glucose and lipid metabolism. However, the signaling pathways that mediate the …

Adiponectin secreted from adipocytes binds to adiponectin receptors AdipoR1 and AdipoR2,
and exerts antidiabetic effects via activation of AMPK and PPAR-α pathways, respectively. …