Background: A consensus conference on multiple system atrophy (MSA) in 1998 established
criteria for diagnosis that have been accepted widely. Since then, clinical, laboratory, …

We report the results of a consensus conference on the diagnosis of multiple system
atrophy (MSA). We describe the clinical features of the disease, which include four domains: …

Neuritic plaques in the brain of Alzheimer's disease patients are characterized by β-amyloid
deposits associated with a glia-mediated inflammatory response. Non-steroidal anti-…

Background Multiple system atrophy (MSA) is a fatal and still poorly understood degenerative
movement disorder that is characterised by autonomic failure, cerebellar ataxia, and …

There is compelling evidence that Alzheimer's disease (AD) amyloid-β (Aβ) deposition is
associated with a local inflammatory response, which is initiated by the activation of microglia …

The spinocerebellar ataxias (SCAs) are a genetically heterogeneous group of autosomal
dominantly inherited progressive disorders, the clinical hallmark of which is loss of balance …

Purpose: To evaluate response rate, response duration, overall survival (OS), and toxicity in
primary CNS lymphoma (PCNSL) after systemic and intraventricular chemotherapy with …

Epidemiological evidence suggests that nonsteroidal anti-inflammatory drugs (NSAIDs)
decrease the risk for Alzheimer's disease (AD). Certain NSAIDs can activate the peroxisome …

Long-term treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) reduces the risk for
Alzheimer's disease (AD). To determine the mechanisms by which inflammation affects AD …

Machado–Joseph disease (MJD; also called spinocerebellar ataxia type 3) is a dominantly
inherited late-onset neurodegenerative disorder caused by expansion of polyglutamine (…