Expression of Interleukin-1β Converting Enzyme Gene Family and bcl-2 Gene Family in the Rat Brain following Permanent Occlusion of the Middle Cerebral Artery
…, M Hoshimaru, Y Uemura, T Tokime… - Journal of Cerebral …, 1997 - journals.sagepub.com
Recent investigations have been suggesting that some neuronal subpopulations may die via
programmed cell death after focal ischemic injury. To clarify the possible roles of the genes …
programmed cell death after focal ischemic injury. To clarify the possible roles of the genes …
Enhanced poly (ADP-ribosyl) ation after focal ischemia in rat brain
T Tokime, K Nozaki, T Sugino… - Journal of Cerebral …, 1998 - journals.sagepub.com
Nitric oxide from neuronal cells plays detrimental roles in glutamate neurotoxicity and in focal
brain ischemia. Nitric oxide directly damages DNA, and breaks in the DNA strands activate …
brain ischemia. Nitric oxide directly damages DNA, and breaks in the DNA strands activate …
Redox control of neuronal damage during brain ischemia after middle cerebral artery occlusion in the rat: immunohistochemical and hybridization studies of …
Y Takagi, T Tokime, K Nozaki, Y Gon… - Journal of Cerebral …, 1998 - journals.sagepub.com
Thioredoxin (TRX) is a small, multifunctional protein with a redox-active site and multiple
biological functions that include reducing activity for reactive oxygen intermediates. We …
biological functions that include reducing activity for reactive oxygen intermediates. We …
Neuroprotective effect of FK506, an immunosuppressant, on transient global ischemia in gerbil
T Tokime, K Nozaki, H Kikuchi - Neuroscience letters, 1996 - Elsevier
Delayed neuronal death (DND) in CA1 region after transient global ischemia is a well-known
phenomenon, but its mechanism has not been clarified. In order to examine the …
phenomenon, but its mechanism has not been clarified. In order to examine the …
[HTML][HTML] Multinodular and vacuolating neuronal tumor: A case report and literature review
S Shitara, T Tokime, Y Akiyama - Surgical neurology international, 2018 - ncbi.nlm.nih.gov
Background: Multinodular and vacuolated neuronal tumor (MVNT) is a benign neuronal tumor
that is newly recognized as architectural appearance that may be related to ganglion cell …
that is newly recognized as architectural appearance that may be related to ganglion cell …
3-Nitropropionic acid induces poly (ADP-ribosyl) ation and apoptosis related gene expression in the striatum in vivo
T Sugino, K Nozaki, T Tokime, N Hashimoto… - Neuroscience …, 1997 - Elsevier
Impaired energy metabolism plays an important role in neuronal cell death after brain ischemia,
and apoptosis has been implicated in cell death induced by metabolic impairment. In the …
and apoptosis has been implicated in cell death induced by metabolic impairment. In the …
Abnormal magnetization transfer ratios in normal-appearing white matter on conventional MR images of patients with occlusive cerebrovascular disease
…, T Tsuchida, Y Yonekura, T Tokime… - American journal …, 2001 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Chronic hypoperfusion may cause ischemic insult in the
deep white matter. The magnetization transfer phenomenon is associated with the amount …
deep white matter. The magnetization transfer phenomenon is associated with the amount …
Syringomyelia associated with a posterior fossa cyst: Illustration of two cases
T Tokime, S Okamoto, S Yamagata, T Konishi - Journal of neurosurgery, 1997 - thejns.org
Case 1. This 14-year-old girl suffered from progressive numbness around her mouth and right
arm. Computerized tomography scanning revealed hydrocephalus and a large cyst in the …
arm. Computerized tomography scanning revealed hydrocephalus and a large cyst in the …
Transient Ischemic Attack Due to Dissection of the Middle Cerebral Artery—Case Report—
…, J JITO, M SHIRAHATA, T TOKIME… - Neurologia medico …, 2001 - jstage.jst.go.jp
A 57-year-old man presented with a transient ischemic attack due to dissection of the middle
cerebral artery. He suffered total aphasia and clouding of consciousness for several minutes…
cerebral artery. He suffered total aphasia and clouding of consciousness for several minutes…
Recipient targeting for revascularization using pulsed Doppler ultrasonography for the treatment of an intracranial giant aneurysm
S Tani, Y Akiyama, T Tokime, J Taki, E Ogino… - Journal of …, 2011 - thejns.org
Aneurysmal occlusion after blood flow revascularization is a promising management strategy
for the treatment of intracranial giant aneurysms. However, it is necessary to design robust …
for the treatment of intracranial giant aneurysms. However, it is necessary to design robust …