von Willebrand disease (VWD) is a bleeding disorder caused by inherited defects in the
concentration, structure, or function of von Willebrand factor (VWF). VWD is classified into three …

… Budde et al reported 187 cases diagnosed in a German reference laboratory among 5014
plasma samples from patients with bleeding disorders received over a 2-year period. Based …

Normal hemostasis requires von Willebrand factor (VWF) to support platelet adhesion and
aggregation at sites of vascular injury. VWF is a multimeric glycoprotein built from identical …

Background: A quantitative description of bleeding symptoms in type 1 von Willebrand disease
(VWD) has never been reported. Objectives: The aim was to quantitatively evaluate the …

Type 1 von Willebrand disease (VWD) is characterized by a personal and family history of
bleeding coincident with reduced levels of normal plasma von Willebrand factor (VWF). The …

… The Mann–Whitney test (U-test) was used for comparison of the pooled VAD patient group
(BiVAD and LVAD patients considered as one VAD group) with HTX patients or if BiVAD and …

… Bucciarelli performed the analysis of the data from the registry and matched the results with
those from the literature; U. Budde and PJJ van Genderen contributed to the preparation of …

Background— Rotary blood pumps used as left ventricular assist devices (LVADs) allow for
long-term support and may become suitable alternatives to heart transplantation. Effects of …

An acquired hemorrhagic disorder developed in two patients in association with postsplenectomy
thrombocytosis and leukocytosis during the course of the myeloproliferative syndrome. …

Twelve of 19 patients with myeloproliferative disorders showed a decrease of absence of
the largest multimers of plasma von Willebrand factor (vWF) that correlated with elevated …