User profiles for U. Dydak
Ulrike DydakProfessor of Health Sciences, Purdue University Verified email at purdue.edu Cited by 6176 |
Clinical proton MR spectroscopy in central nervous system disorders
A large body of published work shows that proton (hydrogen 1 [ 1 H]) magnetic resonance (MR)
spectroscopy has evolved from a research tool into a clinical neuroimaging modality. …
spectroscopy has evolved from a research tool into a clinical neuroimaging modality. …
Methodological consensus on clinical proton MRS of the brain: Review and recommendations
Proton MRS ( 1 H MRS) provides noninvasive, quantitative metabolite profiles of tissue and
has been shown to aid the clinical management of several brain diseases. Although most …
has been shown to aid the clinical management of several brain diseases. Although most …
Biomarkers of manganese intoxication
Manganese (Mn), upon absorption, is primarily sequestered in tissue and intracellular
compartments. For this reason, blood Mn concentration does not always accurately reflect Mn …
compartments. For this reason, blood Mn concentration does not always accurately reflect Mn …
Schizophrenia: glutathione deficit in cerebrospinal fluid and prefrontal cortex in vivo
…, M Kirsten‐Krüger, CJ Lauer, U Dydak… - European Journal of …, 2000 - Wiley Online Library
Schizophrenia is a major psychiatric disease, which affects the centre of the personality,
with severe problems of perception, cognition as well as affective and social behaviour. In …
with severe problems of perception, cognition as well as affective and social behaviour. In …
GABA concentrations in the human anterior cingulate cortex predict negative BOLD responses in fMRI
The human anterior cingulate cortex (ACC) is part of the default-mode network that shows
predominant negative blood oxygen level–dependent (BOLD) responses in functional …
predominant negative blood oxygen level–dependent (BOLD) responses in functional …
The relationship between aberrant neuronal activation in the pregenual anterior cingulate, altered glutamatergic metabolism, and anhedonia in major depression
… Drs Dydak and Boesiger supervised the MRS protocol optimization and validation and
revised the manuscript; Dr Boesiger also provided the magnetic resonance scanner. Dr Northoff …
revised the manuscript; Dr Boesiger also provided the magnetic resonance scanner. Dr Northoff …
Sensitivity‐encoded spectroscopic imaging
… Then the unfolding matrix U is given by: … U is the unfolding matrix as defined in Eq. [1]
and the sinc-function, centered in the voxel x,y, is periodic according to the reduced FOV. …
and the sinc-function, centered in the voxel x,y, is periodic according to the reduced FOV. …
Big GABA: Edited MR spectroscopy at 24 research sites
Magnetic resonance spectroscopy (MRS) is the only biomedical imaging method that can
noninvasively detect endogenous signals from the neurotransmitter γ-aminobutyric acid (GABA…
noninvasively detect endogenous signals from the neurotransmitter γ-aminobutyric acid (GABA…
In Vivo Measurement of Brain GABA Concentrations by Magnetic Resonance Spectroscopy in Smelters Occupationally Exposed to Manganese
U Dydak, YM Jiang, LL Long, H Zhu… - Environmental …, 2011 - ehp.niehs.nih.gov
Background Exposure to excessive levels of manganese (Mn) is known to induce psychiatric
and motor disorders, including parkinsonian symptoms. Therefore, finding a reliable means …
and motor disorders, including parkinsonian symptoms. Therefore, finding a reliable means …
Pathophysiology of manganese-associated neurotoxicity
… Dydak and Zheng broaden the spectrum of neurotransmitters impaired by Mn exposure
and offers a potentially reliable new marker of Mn-associated early stage neuronal injury. …
and offers a potentially reliable new marker of Mn-associated early stage neuronal injury. …