Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury

…, AR Whitney, DJ Gardner, X Fan… - Proceedings of the …, 2010 - National Acad Sciences
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is epidemic
in the United States, even rivaling HIV/AIDS in its public health impact. The pandemic clone …

[HTML][HTML] Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma

…, HQ Wang, MA Nuno, JE Richardson, X Fan… - Cancer Immunology …, 2013 - Springer
Background This study evaluated the safety and immune responses to an autologous
dendritic cell vaccine pulsed with class I peptides from tumor-associated antigens (TAA) …

The K–Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum

…, D Rochefort, N Byun, N Dupré, J Lu, X Fan… - Nature …, 2002 - nature.com
Peripheral neuropathy associated with agenesis of the corpus callosum (ACCPN) is a severe
sensorimotor neuropathy associated with mental retardation, dysmorphic features and …

Expanded parameters in active surveillance for low-risk papillary thyroid carcinoma: a nonrandomized controlled trial

…, JMS Clair, MM Chen, M Vasquez, X Fan… - JAMA …, 2022 - jamanetwork.com
Importance Unlike for prostate cancer, active surveillance for thyroid cancer has not achieved
wide adoption. The parameters by which this approach is feasible are also not well defined…

Incidence and mortality risk spectrum across aggressive variants of papillary thyroid carcinoma

…, N Ali, C Patio, Y Chen, S Bose, X Fan… - JAMA …, 2020 - jamanetwork.com
Importance While well-differentiated papillary thyroid carcinoma (WDPTC) outcomes have
been well characterized, the prognostic implications of more aggressive variants are far less …

[HTML][HTML] Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection

…, S Müller, MD Rodriguez, K Rezai-Zadeh, X Fan… - PLoS …, 2015 - journals.plos.org
Staphylococcus aureus is a leading cause of skin and soft-tissue infections worldwide. Mice
are the most commonly used animals for modeling human staphylococcal infections. …

Surgical management of primary spinal hemangiopericytomas: an institutional case series and review of the literature

…, D Drazin, M Gates, N Shirzadi, S Banykh, X Fan… - European Spine …, 2013 - Springer
Purpose Hemangiopericytoma (HPC) is a rare tumor of the central nervous system. Primary
spinal occurrence of this tumor is extremely uncommon and cases involving the …

Myxoid glioneuronal tumor, PDGFRA p.K385‐mutant: clinical, radiologic, and histopathologic features

…, MM Poppe, KM Fung, S Sung, C Glenn, X Fan… - Brain …, 2020 - Wiley Online Library
“Myxoid glioneuronal tumor, PDGFRA p.K385‐mutant” is a recently described tumor entity
of the central nervous system with a predilection for origin in the septum pellucidum and a …

[PDF][PDF] Blimp-1 functions as a molecular switch to prevent inflammatory activity in Foxp3+ RORγt+ regulatory T cells

…, S Nadeau, RA Porritt, M Couse, X Fan… - Cell reports, 2018 - cell.com
Foxp3 + regulatory T cells (Treg) are essential modulators of immune responses, but the
molecular mechanisms underlying their function are not fully understood. Here we show that the …

Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile

…, M Sill, DTW Jones, M Kool, SM Pfister, X Fan… - Acta …, 2018 - Springer
The septum pellucidum (“translucent wall”) is a thin, triangular membranous structure that
runs sagittally from the corpus callosum down to the fornix and separates the left and right …