Purpose— To critically review and evaluate the science behind individual eligibility criteria (indication/inclusion
and contraindications/exclusion criteria) for intravenous recombinant …

Background Thrombectomy is currently recommended for eligible patients with stroke who
are treated within 6 hours after the onset of symptoms. Methods We conducted a multicenter, …

The aim of this updated statement is to provide comprehensive and timely evidence-based
recommendations on the prevention of ischemic stroke among survivors of ischemic stroke or …

Background Endovascular therapy is increasingly used after the administration of intravenous
tissue plasminogen activator (t-PA) for patients with moderate-to-severe acute ischemic …

Background Combination antiplatelet therapy with clopidogrel and aspirin may reduce the
rate of recurrent stroke during the first 3 months after a minor ischemic stroke or transient …

Background Limited data are available to guide the choice of a target for the systolic blood-pressure
level when treating acute hypertensive response in patients with intracerebral …

ContextConventional colonoscopy is the best available method for detection of colorectal
cancer; however, it is invasive and not without risk. Computed tomographic colonography (CTC…

Background Traumatic brain injury (TBI) is a major cause of death and disability worldwide.
Progesterone has been shown to improve neurologic outcome in multiple experimental …

Background & Aims: Patients with sphincter of Oddi dysfunction are at high risk of developing
pancreatitis after endoscopic biliary sphincterotomy. Impaired pancreatic drainage caused …

Background The IMS III trial did not show a clinical benefit of endovascular treatment
compared with intravenous alteplase (recombinant tissue plasminogen activator) alone for …