Pretransplantation conditioning influence on the occurrence of cyclosporine or FK-506 neurotoxicity in allogeneic bone marrow transplantation

WS Bartynski, ZR Zeigler… - American journal of …, 2004 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Transplantation conditioning regimens have been shown
to affect the brain imaging appearance in patients with cyclosporine or FK-506 neurotoxicity. …

Desmopressin (d‐DAVP) effects on platelet rheology and von Willebrand factor activities in uremia

ZR Zeigler, A Megaludis… - American journal of …, 1992 - Wiley Online Library
Bleeding times, von Willebrand activities, and platelet retentions were examined before and
following d-DAVP in 13 uremic patients. Shortening of the bleeding time from 16.6 2 2.2 (…

Treatment of myelodysplastic syndromes with 5-azacytidine

J Gryn, ZR Zeigler, RK Shadduck, J Lister… - Leukemia research, 2002 - Elsevier
Patients with myelodysplastic syndromes (MDS) who were anemic and/or thrombocytopenic
were treated with 5-azacytidine (5-AZA) at a dose of 75mg/m 2 per day SQ×7 days. This …

Blood platelet responsivity to acute mental stress.

SB Malkoff, MF Muldoon, ZR Zeigler… - Psychosomatic …, 1993 - journals.lww.com
: To evaluate the effects of mental stress on blood platelet activity, platelet secretion and
aggregation were measured in 40 healthy young men, assigned in a 3: 1 ratio to an …

Variable incidence of cyclosporine and FK-506 neurotoxicity in hematopoeitic malignancies and marrow conditions after allogeneic bone marrow transplantation

WS Bartynski, ZR Zeigler, RK Shadduck, J Lister - Neurocritical care, 2005 - Springer
Introduction: This study examines whether malignant disease under treatment influences
the incidence of cyclosporine or FK-506 neurotoxicity after myeloablative conditioning and …

Phase I study of recombinant interleukin-1 beta in patients undergoing autologous bone marrow transplant for acute myelogenous leukemia

…, K Lilleby, WC Buhles, C Rosenfeld, ZR Zeigler… - 1994 - ashpublications.org
A phase I trial was conducted with recombinant human interleukin-1 beta (rhIL-1 beta) in
patients undergoing autologous bone marrow (BM) transplantation for acute myelogenous …

High-dose intravenous gamma globulin improves responses to single-donor platelets in patients refractory to platelet transfusion

ZR Zeigler, RK Shadduck, CS Rosenfeld, KF Mangan… - 1987 - ashpublications.org
Ten patients, with bone marrow failure or malignant disorders, became refractory to platelet
transfusions using random, as well as partial or fully HLA-matched, single-donor platelets. To …

Apheresis in grade 4 bone marrow transplant associated thrombotic microangiopathy: a case series

…, ZR Zeigler, RK Shadduck, R Nath… - Journal of clinical …, 1996 - Wiley Online Library
Bone marrow transplant‐associated thrombotic microangiopathy (BMT‐TM) ranges in severity
from a self‐limited to a fatal disorder. There has been no specific therapy for this condition. …

Plasminogen activator inhibitor (PAI‐1) antigen levels in primary TTP and secondary TTP post‐bone marrow transplantation

MT Anthony, ZR Zeigler, J Lister… - American journal of …, 1998 - Wiley Online Library
Our objectives were to measure and compare plasminogen activator inhibitor levels (PAI‐1)
in primary adult thrombotic thrombocytopenic purpura (TTP) and in secondary TTP …

Potentiation of carmustine-cranial irradiation-induced myelosuppression by cimetidine

…, RK Shadduck, A Winkelstein, ZR Zeigler… - Archives of internal …, 1982 - jamanetwork.com
In nine patients with glioblastomas, the histamine H2-receptor antagonist cimetidine was
found to augment the myelosuppressive activities of carmustine and cranial irradiation. The …