Finding the missing heritability of complex diseases
…, CN Rotimi, M Slatkin, D Valle, AS Whittemore… - Nature, 2009 - nature.com
Genome-wide association studies have identified hundreds of genetic variants associated
with complex human diseases and traits, and have provided valuable insights into their …
with complex human diseases and traits, and have provided valuable insights into their …
Guidelines for carotid endarterectomy: a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association
J Biller, WM Feinberg, JE Castaldo, AD Whittemore… - Circulation, 1998 - Am Heart Assoc
Few studies have analyzed control of risk factors in a randomized, prospective manner following
carotid endarterectomy. However, a wealth of data are available regarding the general …
carotid endarterectomy. However, a wealth of data are available regarding the general …
Soil organic matter turnover is governed by accessibility not recalcitrance
…, DW Hopkins, AS Gregory, AP Whitmore - Global Change …, 2012 - Wiley Online Library
Mechanisms to mitigate global climate change by sequestering carbon ( C ) in different ‘sinks'
have been proposed as at least temporary measures. Of the major global C pools, …
have been proposed as at least temporary measures. Of the major global C pools, …
[PDF][PDF] REVEL: an ensemble method for predicting the pathogenicity of rare missense variants
…, P Radivojac, SN Thibodeau, AS Whittemore… - The American Journal of …, 2016 - cell.com
The vast majority of coding variants are rare, and assessment of the contribution of rare
variants to complex traits is hampered by low statistical power and limited functional data. …
variants to complex traits is hampered by low statistical power and limited functional data. …
Common variants on chromosome 6p22. 1 are associated with schizophrenia
Schizophrenia, a devastating psychiatric disorder, has a prevalence of 0.5–1%, with high
heritability (80–85%) and complex transmission 1 . Recent studies implicate rare, large, high-…
heritability (80–85%) and complex transmission 1 . Recent studies implicate rare, large, high-…
Localized prostate cancer. Relationship of tumor volume to clinical significance for treatment of prostate cancer
…, FS Freiha, JE McNeal, EA Redwine, AS Whittemore… - Cancer, 1993 - Wiley Online Library
Background. Using the Surveillance, Epidemiology, and End Results Program of the National
Cancer Institute and American total mortality rates, the authors calculated the probability at …
Cancer Institute and American total mortality rates, the authors calculated the probability at …
Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada
AS Whittemore, LN Kolonel, AH Wu… - JNCI: Journal of the …, 1995 - academic.oup.com
Background: International and interethnic differences in prostate cancer incidence suggest
an environmental, potentially modifiable etiology for the disease. Purpose: We conducted a …
an environmental, potentially modifiable etiology for the disease. Purpose: We conducted a …
Suggested standards for reports dealing with lower extremity ischemia
…, KW Johnston, A Karmody, AD Whittemore… - Journal of vascular …, 1986 - Elsevier
Reports in the vascular surgery literature are often difficult to assess and compare with each
other because of poorly defined terms, imprecise categorization, lack of indices for gauging …
other because of poorly defined terms, imprecise categorization, lack of indices for gauging …
[HTML][HTML] Effect of bar-code technology on the safety of medication administration
…, WW Churchill, S Lipsitz, AD Whittemore… - … England Journal of …, 2010 - Mass Medical Soc
Background Serious medication errors are common in hospitals and often occur during order
transcription or administration of medication. To help prevent such errors, technology has …
transcription or administration of medication. To help prevent such errors, technology has …
Multiple regions within 8q24 independently affect risk for prostate cancer
…, LC Pooler, K Ardlie, I Oakley-Girvan, AS Whittemore… - Nature …, 2007 - nature.com
After the recent discovery that common genetic variation in 8q24 influences inherited risk of
prostate cancer, we genotyped 2,973 SNPs in up to 7,518 men with and without prostate …
prostate cancer, we genotyped 2,973 SNPs in up to 7,518 men with and without prostate …