Ultrasonography is a widely accessible imaging technique for the detection of fatty liver, but
the reported accuracy and reliability have been inconsistent across studies. We aimed to …

cohol-induced liver disease but develops in individuals who are not heavy drinkers. NAFLD
is likely to be the most common cause of chronic liver disease in many countries and may …

Context Diabetes mellitus appears to be a risk factor for some cancers, but the effect of
preexisting diabetes on all-cause mortality in newly diagnosed cancer patients is less clear. …

Mammalian genomes are organized into megabase-scale topologically associated
domains (TADs). We demonstrate that disruption of TADs can rewire long-range regulatory …

Background Previous research has suggested that thiazide diuretics and beta-blockers may
promote the development of type 2 diabetes mellitus. However, the results of these studies …

Background: In persons with diabetes, chronic hyperglycemia (assessed by glycosylated
hemoglobin level) is related to the development of microvascular disease; however, the …

The intestinal flora may promote colon tumor formation. Here we explore immunologic
mechanisms of colonic carcinogenesis by a human colonic bacterium, enterotoxigenic …

Background End-stage renal disease in the United States creates a large burden for both
individuals and society as a whole. Efforts to prevent the condition require an understanding of …

Background Fasting glucose is the standard measure used to diagnose diabetes in the United
States. Recently, glycated hemoglobin was also recommended for this purpose. Methods …

OBJECTIVE Overweight and obese individuals are encouraged to lose 5–10% of their body
weight to improve cardiovascular disease (CVD) risk, but data supporting this …