Apoptotic cells have long been considered as intrinsically tolerogenic or unable to elicit
immune responses specific for dead cell-associated antigens. However, multiple stimuli can …

Temperature-sensitive liposomes are considered to be a promising tool to achieve site-specific
delivery of drugs. These liposomes have been prepared using lipids whose membranes …

Recent breakthrough results from immune checkpoint inhibitors (ICI) have paved the way to
a new era of cancer immunotherapy. In particular, inhibition of programmed death-1 (PD-1)/…

BACKGROUND AND PURPOSE: Diffusion-weighted images (DWIs) have been used to study
various diseases, particularly since echo-planar techniques shorten examination time. Our …

Polyamidoamine dendrimers having poly(ethylene glycol) grafts were designed as a novel
drug carrier which possesses an interior for the encapsulation of drugs and a biocompatible …

… -K in cultured L6 myocytes. AMP-K phosphorylation is detected by a phosphospecific antibody.
… These To examine the level of activation of AMP-K in muscle in response to leptin, we …

… Cell-surface PD-L1 expression in H1299 cells was examined with or without Chk1 inhibitor
after IR or PARPi (j, k). Error bars represent the sd of three independent experiments (d–k). …

… (ANS) binding displacement assay, BMS309403 exhibited K i values <2 nM for both mouse
and … In this assay, the endogenous fatty acids palmitic acid and oleic acid exhibited aP2 K i …

Sphingosine-1-phosphate (SPP) has diverse biological functions acting inside cells as a
second messenger to regulate proliferation and survival, and extracellularly, as a ligand for G …

Purpose: It is well known that tumor-infiltrating lymphocytes (TILs) and, to a lesser extent,
peripheral blood lymphocytes from patients with advanced-stage cancer have a poor immune …