To NET or not to NET: current opinions and state of the science regarding the formation of neutrophil extracellular traps

…, J Hahn, A Hidalgo, MH Hoffmann… - Cell Death & …, 2019 - nature.com
Since the discovery and definition of neutrophil extracellular traps (NETs) 14 years ago,
numerous characteristics and physiological functions of NETs have been uncovered. Nowadays, …

The dual role of Reactive Oxygen Species in autoimmune and inflammatory diseases: evidence from preclinical models

MH Hoffmann, HR Griffiths - Free radical biology and medicine, 2018 - Elsevier
Reactive oxygen species (ROS) are created in cells during oxidative phosphorylation by the
respiratory chain in the mitochondria or by the family of NADPH oxidase (NOX) complexes. …

[HTML][HTML] Priorities of action and research for the protection of biodiversity and ecosystem services in continental Ecuador

…, DJ Inclan, P Cuenca, JK Noh, MH Hoffmann… - Biological …, 2022 - Elsevier
Ecuador belongs to the megadiverse countries of the world. However, the high diversity in
species, ecosystems and their services are under threat by land use changes, invasive …

Biogeography of Arabidopsis thaliana (L.) Heynh. (Brassicaceae)

MH Hoffmann - Journal of Biogeography, 2002 - Wiley Online Library
Aim The biogeography of the genetic model plant, Arabidopsis thaliana (L.) Heynh., is studied
using a climatic model of its distribution range. The climatic tolerance or amplitude of A. …

[PDF][PDF] The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts

…, CD Buckley, G Schett, D Mougiakakos, MH Hoffmann - Immunity, 2021 - cell.com
Arthritis typically involves recurrence and progressive worsening at specific predilection
sites, but the checkpoints between remission and persistence remain unknown. Here, we …

[HTML][HTML] Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases

…, Q Braster, O Soehnlein, MH Hoffmann… - Cellular & Molecular …, 2021 - nature.com
Excessive release of neutrophil extracellular traps (NETs) is associated with disease severity
and contributes to tissue injury, followed by severe organ damage. Pharmacological or …

Present and potential distribution of invasive garlic mustard (Alliaria petiolata) in North America

E Welk, K Schubert, MH Hoffmann - Diversity and Distributions, 2002 - Wiley Online Library
This paper demonstrates the use of a bioclimatic model mapped over geographical regions
as a tool for spatially refined risk assessment for the establishment of non‐indigenous plants …

[HTML][HTML] Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps

…, M Herrmann, G Schett, R Holmdahl, MH Hoffmann - JCI insight, 2017 - ncbi.nlm.nih.gov
Hoffmann 1 … Hoffmann supervised the project, planned experiments, conducted data
analysis, and wrote the manuscript. All authors read and approved the manuscript. …

[PDF][PDF] Neutrophil extracellular traps initiate gallstone formation

…, T Dumych, Y Zhao, MF Neurath, MH Hoffmann… - Immunity, 2019 - cell.com
… LEM, SB, RB, CS, AM, and MH conceived and coordinated all experiments and conducted
data analysis. NW, ML, EB, VK, and MFN collected, categorized, and provided gallstones and …

In and out of the Qinghai‐Tibet Plateau: divergence time estimation and historical biogeography of the large arctic‐alpine genus Saxifraga L.

…, I Michalak, N Tkach, MH Hoffmann… - Journal of …, 2017 - Wiley Online Library
Aim Geologically dynamic areas often harbour remarkable levels of biodiversity. Among other
factors, mountain building is assumed to be a precondition for species radiation, and yet, …