Modeling tracer kinetics in dynamic Gd‐DTPA MR imaging
PS Tofts - Journal of magnetic resonance imaging, 1997 - Wiley Online Library
Three major models (from Tofts, Larsson, and Brix) for collecting and analyzing dynamic MRI
gadolinium‐diethylenetriamine penta‐acetic acid (Gd‐DTPA) data are examined. All models …
gadolinium‐diethylenetriamine penta‐acetic acid (Gd‐DTPA) data are examined. All models …
[HTML][HTML] Assessment of blood–brain barrier disruption using dynamic contrast-enhanced MRI. A systematic review
AK Heye, RD Culling, MCV Hernández… - NeuroImage: Clinical, 2014 - Elsevier
There is increasing recognition of the importance of blood–brain barrier (BBB) disruption in
aging, dementia, stroke and multiple sclerosis in addition to more commonly-studied …
aging, dementia, stroke and multiple sclerosis in addition to more commonly-studied …
[HTML][HTML] Blood–brain barrier modulation to improve glioma drug delivery
H Luo, EV Shusta - Pharmaceutics, 2020 - mdpi.com
The blood–brain barrier (BBB) is formed by brain microvascular endothelial cells that are
sealed by tight junctions, making it a significant obstacle for most brain therapeutics. The …
sealed by tight junctions, making it a significant obstacle for most brain therapeutics. The …
[HTML][HTML] Blood-brain barrier permeability following conventional photon radiotherapy–A systematic review and meta-analysis of clinical and preclinical studies
Z Odé, MPP Derieppe, L Groenink… - Clinical and …, 2022 - Elsevier
Radiotherapy (RT) is a cornerstone treatment strategy for brain tumours. Besides
cytotoxicity, RT can cause disruption of the blood–brain barrier (BBB), resulting in an …
cytotoxicity, RT can cause disruption of the blood–brain barrier (BBB), resulting in an …
Changes in blood-brain barrier permeability induced by radiotherapy: implications for timing of chemotherapy?
M van Vulpen, HB Kal, MJB Taphoorn… - Oncology …, 2002 - spandidos-publications.com
The brain requires a stable internal environment, which is established by the integrity of the
blood-brain barrier (BBB). The efficacy of chemotherapeutics in the treatment of brain …
blood-brain barrier (BBB). The efficacy of chemotherapeutics in the treatment of brain …
Dynamic contrast‐enhanced MRI using Gd‐DTPA: interindividual variability of the arterial input function and consequences for the assessment of kinetics in tumors
Gd‐DTPA kinetics in arterial blood was investigated by dynamic MRI in 47 patients with
malignant and benign mammary tumors. Signal enhancement was monitored for 10 min …
malignant and benign mammary tumors. Signal enhancement was monitored for 10 min …
Use of magnetic resonance imaging to assess blood-brain/blood-glioma barrier opening during conformal radiotherapy
Y Cao, CI Tsien, Z Shen, DS Tatro… - Journal of Clinical …, 2005 - ascopubs.org
Purpose For chemotherapy to act synergistically and safely with radiation against high-
grade gliomas, drugs must pass the endothelial junctions of the blood-tumor barrier (BTB) to …
grade gliomas, drugs must pass the endothelial junctions of the blood-tumor barrier (BTB) to …
Treatment-induced leukoencephalopathy in primary CNS lymphoma: a clinical and autopsy study
R Lai, LE Abrey, MK Rosenblum, LM DeAngelis - Neurology, 2004 - AAN Enterprises
Background: Treatment-related leukoencephalopathy is the leading toxicity after successful
treatment of primary CNS lymphoma (PCNSL). Its mechanism is poorly understood and …
treatment of primary CNS lymphoma (PCNSL). Its mechanism is poorly understood and …
Multicompartment analysis of gadolinium chelate kinetics: blood‐tissue exchange in mammary tumors as monitored by dynamic MR imaging
The blood‐tissue exchange kinetics of gadopentetate were studied in 49 malignant and
benign mammary tumors. Signal enhancement was monitored simultaneously in the aorta …
benign mammary tumors. Signal enhancement was monitored simultaneously in the aorta …
Diffusion tensor imaging screening of radiation-induced changes in the white matter after prophylactic cranial irradiation of patients with small cell lung cancer: first …
T Welzel, A Niethammer, U Mende… - American Journal …, 2008 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Diffusion tensor imaging (DTI) will show abnormal
fractional anisotropy (FA) in the normal-appearing brain after prophylactic cranial irradiation …
fractional anisotropy (FA) in the normal-appearing brain after prophylactic cranial irradiation …