The image contrast in magnetic resonance imaging (MRI) is highly sensitive to several
mechanisms that are modulated by the properties of the tissue environment. The degree and …

Multiple sclerosis (MS) is a chronic, progressive disorder of the central nervous system
(CNS) that affects more than two million people worldwide. Several animal models resemble …

Magnetic resonance imaging (MRI) monitoring of disease progression in multiple sclerosis
is limited by the lack of correlation of abnormalities seen on T2‐weighted imaging, and …

Postmortem unfixed whole brains from five multiple sclerosis (MS) patients were examined
by MRI using a T2-and T1-weighted spin-echo (SE) sequence and histology to investigate …

The ability to measure myelin in vivo has great consequences for furthering our knowledge
of normal development, as well as for understanding a wide range of neurological disorders …

Objective: The study was undertaken to determine the pathologic basis of subtle
abnormalities in magnetization transfer ratio (MTR) and diffusion tensor imaging (DTI) …

Myelin is critical in maintaining electrical impulse conduction in the central nervous system.
The oligodendrocyte is the cell type responsible for myelin production within this …

T2 weighting is particularly sensitive, but notoriously unspecific, to a wide range of brain
pathologies. However, careful measurement and analysis of the T2 decay curve from brain …

Serial monthly magenetization transfer (MT) imaging was performed to evaluate whether a
change of the normal appearing white matter (NAWM), which precedes the appearance of …

The term hepatic encephalopathy (HE) includes a spectrum of neuropsychiatric
abnormalities occurring in patients with liver dysfunction. Most cases are associated with …