X-Linked adrenoleukodystrophy (ALD) is a peroxisomal metabolic disorder with a highly
complex clinical presentation. ALD is caused by mutations in the ABCD1 gene, which leads …

Dysmyelinating diseases, or leukodystrophies, encompass a wide spectrum of inherited
neurodegenerative disorders affecting the integrity of myelin in the brain and peripheral …

A number of metabolic disorders that affect the central nervous system can present in
childhood, adolescence or adulthood as a phenocopy of a major psychiatric syndrome such …

Objective: To provide clinical, MRI, and histopathologic findings in a rare white matter
disorder with autosomal dominant inheritance, so-called hereditary diffuse …

Adrenoleukodystrophy is an inherited X-linked peroxisomal disorder that preferentially
affects the adrenal cortex, testes, and brain and may occur at almost any age. Psychiatric …

Background: It is not commonly appreciated that patients with adrenoleukodystrophy (ALD)
can first present in adulthood with psychiatric symptoms. Method: This case study involved a …

X-linked adrenoleukodystrophy (X-ALD) is an inherited disease caused by peroxisomal
dysfunction. X-ALD usually involves the cerebral white matter in an approximately symmetric …

CT and MR imaging showed diffuse changes of the frontal white matter and genu of the
corpus callosum with minimal atrophy and no contrast enhancement in a 41-year-old …

The history of any subspecialty in the field of neuroradiology is often determined by the
prominence of personal figures who contributed to and shaped its creation. There is little …

The work reported in this thesis concerns methods for making measurements of anatomical
and pathological structures as seen in MR images of the human body. Our main focus was …