Classic models for dynamic contrast‐enhanced MRI

SP Sourbron, DL Buckley - NMR in Biomedicine, 2013 - Wiley Online Library
Dynamic contrast‐enhanced MRI (DCE‐MRI) is a functional MRI method where T1‐
weighted MR images are acquired dynamically after bolus injection of a contrast agent. The …

MR perfusion imaging of the brain: techniques and applications

JR Petrella, JM Provenzale - American Journal of …, 2000 - Am Roentgen Ray Soc
Fig. 1.—32-year-old healthy man. Echoplanar images of same slice show bolus of
paramagnetic contrast material passing through tissues. Imaging was performed at rate of …

Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging

M Law, S Yang, H Wang, JS Babb… - American journal …, 2003 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Sensitivity, positive predictive value (PPV), and negative
predictive value (NPV) of conventional MR imaging in predicting glioma grade are not high …

Comparison of cerebral blood volume and vascular permeability from dynamic susceptibility contrast-enhanced perfusion MR imaging with glioma grade

M Law, S Yang, JS Babb, EA Knopp… - American Journal …, 2004 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Relative cerebral blood volume (rCBV) and vascular
permeability (Ktrans) permit in vivo assessment of glioma microvasculature. We assessed …

Differentiation of recurrent glioblastoma multiforme from radiation necrosis after external beam radiation therapy with dynamic susceptibility-weighted contrast …

RF Barajas Jr, JS Chang, MR Segal, AT Parsa… - Radiology, 2009 - pubs.rsna.org
Purpose To investigate whether cerebral blood volume (CBV), peak height (PH), and
percentage of signal intensity recovery (PSR) measurements derived from the results of T2 …

Posttherapeutic intraaxial brain tumor: the value of perfusion-sensitive contrast-enhanced MR imaging for differentiating tumor recurrence from nonneoplastic contrast …

T Sugahara, Y Korogi, S Tomiguchi… - American Journal …, 2000 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Differentiation of tumor recurrence from treatment-related
changes may be difficult with conventional MR imaging when newly enhancing lesions …

Relative cerebral blood volume values to differentiate high-grade glioma recurrence from posttreatment radiation effect: direct correlation between image-guided …

LS Hu, LC Baxter, KA Smith… - American Journal …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Differentiating tumor growth from posttreatment radiation
effect (PTRE) remains a common problem in neuro-oncology practice. To our knowledge …

Comparison of dynamic susceptibility-weighted contrast-enhanced MR methods: recommendations for measuring relative cerebral blood volume in brain tumors

ES Paulson, KM Schmainda - Radiology, 2008 - pubs.rsna.org
Purpose: To investigate whether estimates of relative cerebral blood volume (rCBV) in brain
tumors, obtained by using dynamic susceptibility-weighted contrast material–enhanced …

Quantification of cerebral blood flow, cerebral blood volume, and blood–brain‐barrier leakage with DCE‐MRI

S Sourbron, M Ingrisch, A Siefert… - … in Medicine: An …, 2009 - Wiley Online Library
Dynamic susceptibility contrast MRI (DSC‐MRI) is the current standard for the measurement
of Cerebral Blood Flow (CBF) and Cerebral Blood Volume (CBV), but it is not suitable for the …

Measurement of brain perfusion, blood volume, and blood‐brain barrier permeability, using dynamic contrast‐enhanced T1‐weighted MRI at 3 tesla

HBW Larsson, F Courivaud, E Rostrup… - … in Medicine: An …, 2009 - Wiley Online Library
Assessment of vascular properties is essential to diagnosis and follow‐up and basic
understanding of pathogenesis in brain tumors. In this study, a procedure is presented that …