Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke …

PB Gorelick, A Scuteri, SE Black, C DeCarli… - stroke, 2011 - Am Heart Assoc
Background and Purpose—This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …

Cerebral hemorrhage: pathophysiology, treatment, and future directions

J Magid-Bernstein, R Girard, S Polster… - Circulation …, 2022 - Am Heart Assoc
Intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity and
mortality. This review article focuses on the epidemiology, cause, mechanisms of injury …

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

JM Wardlaw, EE Smith, GJ Biessels… - The Lancet …, 2013 - thelancet.com
Cerebral small vessel disease (SVD) is a common accompaniment of ageing. Features seen
on neuroimaging include recent small subcortical infarcts, lacunes, white matter …

Cerebral microbleeds: a guide to detection and interpretation

SM Greenberg, MW Vernooij, C Cordonnier… - The Lancet …, 2009 - thelancet.com
Cerebral microbleeds (CMBs) are increasingly recognised neuroimaging findings in
individuals with cerebrovascular disease and dementia, and in normal ageing. There has …

National Institute of Neurological Disorders and Stroke–Canadian stroke network vascular cognitive impairment harmonization standards

V Hachinski, C Iadecola, RC Petersen, MM Breteler… - Stroke, 2006 - Am Heart Assoc
Background and Purpose—One in 3 individuals will experience a stroke, dementia or both.
Moreover, twice as many individuals will have cognitive impairment short of dementia as …

Emerging concepts in sporadic cerebral amyloid angiopathy

A Charidimou, G Boulouis, ME Gurol, C Ayata… - Brain, 2017 - academic.oup.com
Sporadic cerebral amyloid angiopathy is a common, well-defined small vessel disease and
a largely untreatable cause of intracerebral haemorrhage and contributor to age-related …

Inflammation and cerebral small vessel disease: a systematic review

A Low, E Mak, JB Rowe, HS Markus, JT O'Brien - Ageing research reviews, 2019 - Elsevier
Inflammation is increasingly implicated as a risk factor for dementia, stroke, and small vessel
disease (SVD). However, the underlying mechanisms and causative pathways remain …

Heterogeneity of small vessel disease: a systematic review of MRI and histopathology correlations

AA Gouw, A Seewann, WM Van Der Flier… - Journal of Neurology …, 2011 - jnnp.bmj.com
Background White matter hyperintensities (WMH), lacunes and microbleeds are regarded as
typical MRI expressions of cerebral small vessel disease (SVD) and they are highly …

[HTML][HTML] Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer's disease

RN Kalaria - Acta neuropathologica, 2016 - Springer
Vascular dementia (VaD) is recognised as a neurocognitive disorder, which is explained by
numerous vascular causes in the general absence of other pathologies. The heterogeneity …

The pathology and pathophysiology of vascular dementia

RN Kalaria - Neuropharmacology, 2018 - Elsevier
Vascular dementia (VaD) is widely recognised as the second most common type of
dementia. Consensus and accurate diagnosis of clinically suspected VaD relies on wide …