Calvarial abnormalities are usually discovered incidentally on radiologic studies or less
commonly manifest with symptoms. This narrative review describes the imaging spectrum of …

Tuberous sclerosis complex (TSC) is due to pathogenic variants in TSC1 or TSC2 genes
resulting in hyperactivation of the mTOR pathway. Many organ systems can be affected …

Insulin signaling in osteoblasts regulates global energy balance by stimulating the
production of osteocalcin, a bone-derived protein that promotes insulin production and …

Tuberous sclerosis complex (TSC) is due to pathogenic variants in TSC1 or TSC2 genes
resulting in hyperactivation of the mTOR pathway. Many organ systems can be affected …

Opacification of the middle ear and mastoid represents a spectrum of inflammatory,
neoplastic, vascular, fibro-osseous, and traumatic changes. This article reviews the most …

Publisher Summary Recognition of fibrous dysplasia (FD) as a distinct skeletal disease is
commonly attributed to the description of an osteitis fibrosa disseminata occurring in …

Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized
by benign hamartomas in multiple organ systems, primarily the skin, brain, heart, kidneys …

An 18-month-old boy presented with a swelling on his back, global developmental delay,
and seizures. At birth, he had a tuft of hair on his left lower back which developed into an ill …

We report an unusual and extremely rare case of coexisting fibrous dysplasia of the
sphenoid sinus with atypical lymphoplasmacyte rich meningioma (World Health …

Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous disorder
characterized principally by multiorgan development of benign tumors and hamartomas …