N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology
JR Moffett, B Ross, P Arun, CN Madhavarao… - Progress in …, 2007 - Elsevier
The brain is unique among organs in many respects, including its mechanisms of lipid
synthesis and energy production. The nervous system-specific metabolite N-acetylaspartate …
synthesis and energy production. The nervous system-specific metabolite N-acetylaspartate …
Clinical proton MR spectroscopy in central nervous system disorders
A large body of published work shows that proton (hydrogen 1 [1H]) magnetic resonance
(MR) spectroscopy has evolved from a research tool into a clinical neuroimaging modality …
(MR) spectroscopy has evolved from a research tool into a clinical neuroimaging modality …
Astrocyte biomarkers in Alzheimer's disease
Astrocytic contributions to Alzheimer's disease (AD) progression were, until recently, largely
overlooked. Astrocytes are integral to normal brain function and astrocyte reactivity is an …
overlooked. Astrocytes are integral to normal brain function and astrocyte reactivity is an …
In vivo 1H NMR spectroscopy of the human brain at high magnetic fields: Metabolite quantification at 4T vs. 7T
A comprehensive comparative study of metabolite quantification from the human brain was
performed on the same 10 subjects at 4T and 7T using MR scanners with identical consoles …
performed on the same 10 subjects at 4T and 7T using MR scanners with identical consoles …
MR spectroscopic imaging: principles and recent advances
MR spectroscopic imaging (MRSI) has become a valuable tool for quantifying metabolic
abnormalities in human brain, prostate, breast and other organs. It is used in routine clinical …
abnormalities in human brain, prostate, breast and other organs. It is used in routine clinical …
Imaging artifacts at 3.0 T
MA Bernstein, J Huston III… - Journal of Magnetic …, 2006 - Wiley Online Library
Clinical MRI at a field strength of 3.0 T is finding increasing use. However, along with the
advantages of 3.0 T, such as increased SNR, there can be drawbacks, including increased …
advantages of 3.0 T, such as increased SNR, there can be drawbacks, including increased …
A review of MR physics: 3T versus 1.5 T
This article illustrates changes in the underlying physics concepts related to increasing the
main magnetic field from 1.5 T to 3T. The effects of these changes on tissue constants and …
main magnetic field from 1.5 T to 3T. The effects of these changes on tissue constants and …
The role of Smo-Shh/Gli signaling activation in the prevention of neurological and ageing disorders
Sonic hedgehog (Shh) signaling is an essential central nervous system (CNS) pathway
involved during embryonic development and later life stages. Further, it regulates cell …
involved during embryonic development and later life stages. Further, it regulates cell …
[HTML][HTML] Molecular and imaging biomarkers in Alzheimer's disease: a focus on recent insights
Alzheimer's disease (AD) is the most common neurodegenerative disease among the
elderly, affecting millions of people worldwide and clinically characterized by a progressive …
elderly, affecting millions of people worldwide and clinically characterized by a progressive …
Reduced hippocampal glutamate in Alzheimer disease
R Rupsingh, M Borrie, M Smith, JL Wells, R Bartha - Neurobiology of aging, 2011 - Elsevier
Altered neurometabolic profiles have been detected in Alzheimer disease (AD) using 1H
magnetic resonance spectroscopy (MRS), but no definitive biomarker of mild cognitive …
magnetic resonance spectroscopy (MRS), but no definitive biomarker of mild cognitive …