Targeted delivery of antibody-based therapeutic and imaging agents to CNS tumors: crossing the blood–brain barrier divide

AM Chacko, C Li, DA Pryma, S Brem… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Brain tumors are inherently difficult to treat in large part due to the cellular blood–
brain barriers (BBBs) that limit the delivery of therapeutics to the tumor tissue from the …

Update on ocular complications of systemic cancer chemotherapy

KE Schmid, GV Kornek, W Scheithauer… - Survey of ophthalmology, 2006 - Elsevier
The constantly growing list of cytotoxic chemotherapeutics requires a new survey of
ophthalmic complications, which are often underestimated. Based on the review by Imperia …

Side by side comparison between dynamic versus static models of blood–brain barrier in vitro: a permeability study

S Santaguida, D Janigro, M Hossain, E Oby, E Rapp… - Brain research, 2006 - Elsevier
Endothelial cells in vivo are continuously exposed to shear stress, a tangential force
generated by the flow of blood across their apical surfaces that affects endothelial cell …

Enhanced chemotherapy delivery by intraarterial infusion and blood‐brain barrier disruption in the treatment of cerebral metastasis

D Fortin, C Gendron, M Boudrias… - … International Journal of …, 2007 - Wiley Online Library
BACKGROUND. Cerebral metastases are clinically significant in 10% to 30% of patients
with neoplasia. Multiple cerebral metastases are typically treated with palliative …

Contributions of drug transporters to blood-brain barriers

L Liu, X Liu - Drug Transporters in Drug Disposition, Effects and …, 2019 - Springer
Blood-brain interfaces comprise the cerebral microvessel endothelium forming the blood-
brain barrier (BBB) and the epithelium of the choroid plexuses forming the blood …

Maculopathy in patients with primary CNS lymphoma treated with chemotherapy in conjunction with blood–brain barrier disruption

J Vicuna-Kojchen, S Frenkel, T Siegal… - British journal of …, 2008 - bjo.bmj.com
Aim: To determine the incidence and characteristics of maculopathy associated with blood–
brain barrier disruption (BBBD) which is used in treating primary central nervous system …

Risk factors for idiopathic orbital inflammation: a case–control study

WR Bijlsma, CH van Gils, D Paridaens… - British journal of …, 2011 - bjo.bmj.com
Objective To identify risk factors involved in the development of idiopathic orbital
inflammation (IOI). Methods Case–control study of 69 adults who had had a first episode of …

Idiopathic (non-specific) orbital inflammation

K Mulay, SG Honavar - Diagnostic Histopathology, 2015 - Elsevier
Orbital inflammatory disease is a broad spectrum of orbital diseases comprising of infections
and inflammations which may pose potential threat to life and/or vision. It is difficult for the …

[PDF][PDF] ĐIỀU TRỊ GIẢ U VIÊM HỐC MẮT BẰNG CYCLOSPORINE A

PT VĂN - lib.yhn.edu.vn
Giả u viêm hốc mắt là tình trạng viêm tổ chức hốc mắt không rõ nguyên nhân, đáp ứng với
điều trị bằng corticoide. Tuy nhiên, điều trị bệnh sẽ gặp khó khăn khi bệnh nhân kháng hay …

全脑常规照射对血脑屏障功能影响的实验研究

曹远东, 章龙珍, 陈勇, 董红燕, 于红丽… - 中华放射医学与防护杂志, 2008 - cqvip.com
目的探讨全脑常规照射对大鼠血脑屏障(BBB) 功能的影响. 方法采用^ 60Coγ 射线对SD
大鼠进行不同剂量的全脑常规外照射, 照射后16h, 静脉给予甲氨蝶呤(MTX) …