Clinical neurology and epidemiology of the major neurodegenerative diseases

MG Erkkinen, MO Kim… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …

A review on neuroimaging-based classification studies and associated feature extraction methods for Alzheimer's disease and its prodromal stages

S Rathore, M Habes, MA Iftikhar, A Shacklett… - NeuroImage, 2017 - Elsevier
Neuroimaging has made it possible to measure pathological brain changes associated with
Alzheimer's disease (AD) in vivo. Over the past decade, these measures have been …

Hierarchical feature representation and multimodal fusion with deep learning for AD/MCI diagnosis

HI Suk, SW Lee, D Shen… - NeuroImage, 2014 - Elsevier
For the last decade, it has been shown that neuroimaging can be a potential tool for the
diagnosis of Alzheimer's Disease (AD) and its prodromal stage, Mild Cognitive Impairment …

Multi-modality cascaded convolutional neural networks for Alzheimer's disease diagnosis

M Liu, D Cheng, K Wang, Y Wang… - Neuroinformatics, 2018 - Springer
Accurate and early diagnosis of Alzheimer's disease (AD) plays important role for patient
care and development of future treatment. Structural and functional neuroimages, such as …

Early-onset Alzheimer disease

MF Mendez - Neurologic clinics, 2017 - neurologic.theclinics.com
Alzheimer disease (AD) originally meant a disorder of early-onset (EOAD;< 65 years of age)
and did not include older patients with “senile dementia.” In fact, the first patient reported …

Neuroimaging correlates of pathologically defined subtypes of Alzheimer's disease: a case-control study

JL Whitwell, DW Dickson, ME Murray… - The Lancet …, 2012 - thelancet.com
Summary Background Three subtypes of Alzheimer's disease (AD) have been
pathologically defined on the basis of the distribution of neurofibrillary tangles: typical AD …

3D maps from multiple MRI illustrate changing atrophy patterns as subjects progress from mild cognitive impairment to Alzheimer's disease

JL Whitwell, SA Przybelski, SD Weigand, DS Knopman… - Brain, 2007 - academic.oup.com
Mild cognitive impairment (MCI), particularly the amnestic subtype (aMCI), is considered as
a transitional stage between normal aging and a diagnosis of clinically probable Alzheimer's …

[HTML][HTML] Visual assessment of posterior atrophy development of a MRI rating scale

ELGE Koedam, M Lehmann, WM van der Flier… - European …, 2011 - Springer
Objective To develop a visual rating scale for posterior atrophy (PA) assessment and to
analyse whether this scale aids in the discrimination between Alzheimer's disease (AD) and …

Ensemble sparse classification of Alzheimer's disease

M Liu, D Zhang, D Shen… - NeuroImage, 2012 - Elsevier
The high-dimensional pattern classification methods, eg, support vector machines (SVM),
have been widely investigated for analysis of structural and functional brain images (such as …

Mild Cognitive Impairment and Alzheimer Disease: Patterns of Altered Cerebral Blood Flow at MR Imaging1

W Dai, OL Lopez, OT Carmichael, JT Becker, LH Kuller… - Radiology, 2009 - pubs.rsna.org
Purpose: To examine regional cerebral blood flow (rCBF) in incident mild cognitive
impairment (MCI) and Alzheimer disease (AD) by using continuous arterial spin-labeling …