[HTML][HTML] The value of magnetic resonance imaging as a biomarker for amyotrophic lateral sclerosis: a systematic review

G Grolez, C Moreau, V Danel-Brunaud, C Delmaire… - BMC neurology, 2016 - Springer
Background Amyotrophic lateral sclerosis (ALS) is a fatal, rapidly progressive
neurodegenerative disease that mainly affects the motor system. A number of potentially …

The present and the future of neuroimaging in amyotrophic lateral sclerosis

F Agosta, A Chiň, M Cosottini… - American journal …, 2010 - Am Soc Neuroradiology
In patients with ALS, conventional MR imaging is frequently noninformative, and its use has
been restricted to excluding other conditions that can mimic ALS. Conversely, the extensive …

Integrated magnetic resonance imaging and [11C]‐PBR28 positron emission tomographic imaging in amyotrophic lateral sclerosis

MJ Alshikho, NR Zürcher, ML Loggia… - Annals of …, 2018 - Wiley Online Library
Objective To characterize [11C]‐PBR28 brain uptake using positron emission tomography
(PET) in people with amyotrophic lateral sclerosis (ALS) and primary lateral sclerosis (PLS) …

Assessment of white matter tract damage in patients with amyotrophic lateral sclerosis: a diffusion tensor MR imaging tractography study

F Agosta, E Pagani, M Petrolini… - American Journal …, 2010 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Most DTI studies in ALS have been limited to the
assessment of the CST damage. In this study, we used DTI tractography to investigate …

Neuroimaging in amyotrophic lateral sclerosis

MR Turner, F Agosta, P Bede, V Govind… - Biomarkers in …, 2012 - Future Medicine
The catastrophic system failure in amyotrophic lateral sclerosis is characterized by
progressive neurodegeneration within the corticospinal tracts, brainstem nuclei and spinal …

Diffusional kurtosis imaging of the developing brain

A Paydar, E Fieremans, JI Nwankwo… - American Journal …, 2014 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Diffusional kurtosis imaging is an extension of DTI but
includes non-Gaussian diffusion effects, allowing more comprehensive characterization of …

Sensorimotor functional connectivity changes in amyotrophic lateral sclerosis

F Agosta, P Valsasina, M Absinta, N Riva… - Cerebral …, 2011 - academic.oup.com
We investigated whether the functional connections to the primary sensorimotor cortex
(SMC) at rest are abnormal in 26 patients with amyotrophic lateral sclerosis (ALS) and …

Diffusion-MRI in neurodegenerative disorders

J Goveas, L O'Dwyer, M Mascalchi, M Cosottini… - Magnetic resonance …, 2015 - Elsevier
The ability to image the whole brain through ever more subtle and specific
methods/contrasts has come to play a key role in understanding the basis of brain …

[HTML][HTML] Imaging biomarkers for the diagnosis and prognosis of neurodegenerative diseases. The example of amyotrophic lateral sclerosis

M Mazón, JF Vázquez Costa, A Ten-Esteve… - Frontiers in …, 2018 - frontiersin.org
The term amyotrophic lateral sclerosis (ALS) comprises a heterogeneous group of fatal
neurodegenerative disorders of largely unknown etiology characterized by the upper motor …

Reliability of fiber tracking measurements in diffusion tensor imaging for longitudinal study

LE Danielian, NK Iwata, DM Thomasson, MK Floeter - Neuroimage, 2010 - Elsevier
The statistical reliability of diffusion property measurements was evaluated in ten healthy
subjects using deterministic fiber tracking to localize tracts affected in motor neuron disease …