High WSS or low WSS? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture: toward a unifying hypothesis
Increasing detection of unruptured intracranial aneurysms, catastrophic outcomes from
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …
Unruptured intracranial aneurysms: development, rupture and preventive management
N Etminan, GJ Rinkel - Nature Reviews Neurology, 2016 - nature.com
Saccular unruptured intracranial aneurysms (UIAs) have a prevalence of 3% in the adult
population, and are being increasingly detected because of improved quality and higher …
population, and are being increasingly detected because of improved quality and higher …
Guidelines for the management of patients with unruptured intracranial aneurysms: a guideline for healthcare professionals from the American Heart Association …
BG Thompson, RD Brown Jr, S Amin-Hanjani… - Stroke, 2015 - Am Heart Assoc
Purpose—The aim of this updated statement is to provide comprehensive and evidence-
based recommendations for management of patients with unruptured intracranial …
based recommendations for management of patients with unruptured intracranial …
Review of cerebral aneurysm formation, growth, and rupture
Figure. Cerebral aneurysm (CA) formation and rupture. Aneurysm formation is initiated by
hemodynamically triggered endothelial dysfunction. An inflammatory response implicating …
hemodynamically triggered endothelial dysfunction. An inflammatory response implicating …
Artificial intelligence velocimetry reveals in vivo flow rates, pressure gradients, and shear stresses in murine perivascular flows
KAS Boster, S Cai… - Proceedings of the …, 2023 - National Acad Sciences
Quantifying the flow of cerebrospinal fluid (CSF) is crucial for understanding brain waste
clearance and nutrient delivery, as well as edema in pathological conditions such as stroke …
clearance and nutrient delivery, as well as edema in pathological conditions such as stroke …
[HTML][HTML] An attention residual u-net with differential preprocessing and geometric postprocessing: Learning how to segment vasculature including intracranial …
Objective Intracranial aneurysms (IA) are lethal, with high morbidity and mortality rates.
Reliable, rapid, and accurate segmentation of IAs and their adjacent vasculature from …
Reliable, rapid, and accurate segmentation of IAs and their adjacent vasculature from …
Aneurysm formation, growth, and rupture: the biology and physics of cerebral aneurysms
Cerebral aneurysms (CAs) are characterized by a pathological wall structure with internal
elastic lamina and media disruption, which leads to focal weakened pouches of the arterial …
elastic lamina and media disruption, which leads to focal weakened pouches of the arterial …
Hemodynamic stress, inflammation, and intracranial aneurysm development and rupture: a systematic review
F Signorelli, S Sela, L Gesualdo, S Chevrel, F Tollet… - World neurosurgery, 2018 - Elsevier
Background There seems to be a pathogenetic link between hemodynamics and
inflammatory arterial wall alteration leading to the development and rupture of intracranial …
inflammatory arterial wall alteration leading to the development and rupture of intracranial …
What does computational fluid dynamics tell us about intracranial aneurysms? A meta-analysis and critical review
Despite the plethora of published studies on intracranial aneurysms (IAs) hemodynamic
using computational fluid dynamics (CFD), limited progress has been made towards …
using computational fluid dynamics (CFD), limited progress has been made towards …
Vessel wall enhancement in unruptured intracranial aneurysms: an indicator for higher risk of rupture? High-resolution MR imaging and correlated histologic findings
N Larsen, C Von Der Brelie, D Trick… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Recent studies have suggested that wall enhancement of
unruptured intracranial aneurysms in high-resolution MR imaging might serve as an imaging …
unruptured intracranial aneurysms in high-resolution MR imaging might serve as an imaging …