[HTML][HTML] Protective effects of cannabidiol against seizures and neuronal death in a rat model of mesial temporal lobe epilepsy

RA Do Val-da Silva, JE Peixoto-Santos… - Frontiers in …, 2017 - frontiersin.org
The present study reports the behavioral, electrophysiological, and neuropathological
effects of cannabidiol (CBD), a major non-psychotropic constituent of Cannabis sativa, in the …

Tract‐specific atrophy in focal epilepsy: disease, genetics, or seizures?

DN Vaughan, D Raffelt, E Curwood, MH Tsai… - Annals of …, 2017 - Wiley Online Library
Objective To investigate whether genetics, underlying pathology, or repeated seizures
contribute to atrophy in specific white matter tracts. Methods Medically refractory unilateral …

The frequency of spontaneous seizures in rats correlates with alterations in sensorimotor gating, spatial working memory, and parvalbumin expression throughout …

DC Wolf, LS Bueno-Junior, C Lopes-Aguiar… - Neuroscience, 2016 - Elsevier
Cognitive deficits and psychotic symptoms are highly prevalent in patients with temporal
lobe epilepsy (TLE). Imaging studies in humans have suggested that these comorbidities …

Neuropathology in the North American sudden unexpected death in epilepsy registry

DF Leitner, A Faustin, C Verducci… - Brain …, 2021 - academic.oup.com
Sudden unexpected death in epilepsy is the leading category of epilepsy-related death and
the underlying mechanisms are incompletely understood. Risk factors can include a recent …

Adhesio interthalamica and cavum septum pellucidum in mesial temporal lobe epilepsy

C Trzesniak, IM Linares, ÉR Coimbra, AV Júnior… - Brain imaging and …, 2016 - Springer
The absence of the adhesio interthalamica (AI; also called interthalamic adhesion or massa
intermedia) and the presence of a large cavum septum pellucidum (CSP) later in life have …

Quantitative multi-modal MRI of the Hippocampus and cognitive ability in community-dwelling older subjects

BS Aribisala, NA Royle, SM Maniega, MCV Hernández… - Cortex, 2014 - Elsevier
Hippocampal structural integrity is commonly quantified using volumetric measurements
derived from brain magnetic resonance imaging (MRI). Previously reported associations …

[HTML][HTML] MRI segmentation analysis in temporal lobe and idiopathic generalized epilepsy

H Goldberg, A Weinstock, N Bergsland, MG Dwyer… - BMC neurology, 2014 - Springer
Background Temporal lobe epilepsy (TLE) and idiopathic generalized epilepsy (IGE)
patients have each been associated with extensive brain atrophy findings, yet to date there …

Magnetisation transfer parameters and stroke outcome

I Sibon, T Tourdias, S Felix, J Asselineau… - Journal of Clinical …, 2015 - Elsevier
Our aim was to evaluate the association between magnetisation transfer imaging (MTI)
parameters measured 30 to 45 days after a cerebrovascular insult and post-stroke functional …

[HTML][HTML] Can MRI T1 be used to detect early changes in 5xFAD Alzheimer's mouse brain?

NG Spencer, DP Lovell, K Elderfield, B Austen… - … Resonance Materials in …, 2017 - Springer
Objectives In the present study, we have tested whether MRI T 1 relaxation time is a
sensitive marker to detect early stages of amyloidosis and gliosis in the young 5xFAD …

[HTML][HTML] Histological correlates of hippocampal magnetization transfer images in drug-resistant temporal lobe epilepsy patients

JE Peixoto-Santos, TR Velasco, CG Carlotti… - NeuroImage: Clinical, 2020 - Elsevier
Objective Temporal lobe epilepsy patients (TLE) often present with hippocampal atrophy,
increased T2 relaxation, and reduced magnetization transfer ratio (MTR) in magnetic …