Patients with the main clinical phenotypes of multiple sclerosis (MS) manifest varying
degrees of brain atrophy beyond that of normal aging. Assessment of atrophy helps to …

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the
central nervous system, characterized by the accumulation of numerous neurological …

Fatigue is the most common and debilitating symptom in multiple sclerosis (MS) and is
believed to be distinctly different from fatigue seen in other chronic conditions. It can affect a …

Background: Fatigue is one of the most frequent and disabling symptoms in multiple
sclerosis, but its pathophysiological mechanisms are poorly understood. It is in particular …

Fatigue is very common in multiple sclerosis (MS) and is often considered as its most
disabling symptom. Over the last 20 years, an increasing number of studies have evaluated …

Multiple sclerosis (MS) is a chronic progressive inflammatory disease of the central nervous
system (CNS) and the major cause of non-traumatic disability in young adults. Fatigue is a …

Cognitive fatigue is one of the most frequent symptoms in multiple sclerosis (MS), associated
with significant impairment in daily functioning and quality of life. Despite its clinical …

Background and purpose The prevalence of fatigue and its relation with clinical,
neuropsychological and brain magnetic resonance imaging (MRI) variables in a large cohort …

Grey matter (GM) damage in Multiple Sclerosis (MS) occurs largely independent of white
matter (WM) lesions and shows stronger correlation with clinical parameters than WM …

Background Fatigue is a common and debilitating symptom in multiple sclerosis (MS). Over
the past decade, a growing body of research has focussed on the pathophysiological …