Integrative regulation of human brain blood flow
Herein, we review mechanisms regulating cerebral blood flow (CBF), with specific focus on
humans. We revisit important concepts from the older literature and describe the interaction …
humans. We revisit important concepts from the older literature and describe the interaction …
[HTML][HTML] 4D flow imaging with MRI
Magnetic resonance imaging (MRI) has become an important tool for the clinical evaluation
of patients with cardiovascular disease. Since its introduction in the late 1980s, 2 …
of patients with cardiovascular disease. Since its introduction in the late 1980s, 2 …
Age‐related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review
The process of aging includes changes in cellular biology that affect local interactions
between cells and their environments and eventually propagate to systemic levels. In the …
between cells and their environments and eventually propagate to systemic levels. In the …
Increased cerebral arterial pulsatility in patients with leukoaraiosis: arterial stiffness enhances transmission of aortic pulsatility
Background and Purpose—Arterial stiffening reduces damping of the arterial waveform and
hence increases pulsatility of cerebral blood flow, potentially damaging small vessels. In the …
hence increases pulsatility of cerebral blood flow, potentially damaging small vessels. In the …
Age, sex, and the vascular contributors to cerebral pulsatility and pulsatile damping
WK Lefferts, JP DeBlois, JA Augustine… - Journal of Applied …, 2020 - journals.physiology.org
Cerebral pulsatility reflects a balance between the transmission and damping of pulsatility in
the cerebrovasculature. Females experience greater cerebral pulsatility with aging, which …
the cerebrovasculature. Females experience greater cerebral pulsatility with aging, which …
Aging alters the dampening of pulsatile blood flow in cerebral arteries
Excessive pulsatile flow caused by aortic stiffness is thought to be a contributing factor for
several cerebrovascular diseases. The main purpose of this study was to describe the …
several cerebrovascular diseases. The main purpose of this study was to describe the …
Changes in intracranial venous blood flow and pulsatility in Alzheimer's disease: a 4D flow MRI study
LA Rivera-Rivera, T Schubert, P Turski… - Journal of Cerebral …, 2017 - journals.sagepub.com
Cerebral blood flow, arterial pulsation, and vasomotion may be important indicators of
cerebrovascular health in aging and diseases of aging such as Alzheimer's disease …
cerebrovascular health in aging and diseases of aging such as Alzheimer's disease …
[HTML][HTML] The impact of aging on the association between aortic stiffness and cerebral pulsatility index
The central arteries dampen the pulsatile forces from myocardial contraction, limiting the
pulsatility that reaches the cerebral vasculature, although there are limited data on this …
pulsatility that reaches the cerebral vasculature, although there are limited data on this …
Narrowing the expertise gap for predicting intracranial aneurysm hemodynamics: impact of solver numerics versus mesh and time-step resolution
MO Khan, K Valen-Sendstad… - American Journal of …, 2015 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Recent high-resolution computational fluid dynamics
studies have uncovered the presence of laminar flow instabilities and possible transitional or …
studies have uncovered the presence of laminar flow instabilities and possible transitional or …
[HTML][HTML] Computed tomographic distinction of intimal and medial calcification in the intracranial internal carotid artery
R Kockelkoren, A Vos, W Van Hecke, A Vink… - PloS one, 2017 - journals.plos.org
Background Intracranial internal carotid artery (iICA) calcification is associated with stroke
and is often seen as a proxy of atherosclerosis of the intima. However, it was recently shown …
and is often seen as a proxy of atherosclerosis of the intima. However, it was recently shown …