Infectious immunity in the central nervous system and brain function

RS Klein, C Garber, N Howard - Nature immunology, 2017 - nature.com
Inflammation is emerging as a critical mechanism underlying neurological disorders of
various etiologies, yet its role in altering brain function as a consequence of neuroinfectious …

CNS–immune reconstitution inflammatory syndrome in the setting of HIV infection, part 1: overview and discussion of progressive multifocal leukoencephalopathy …

MJD Post, MM Thurnher, DB Clifford… - American Journal …, 2013 - Am Soc Neuroradiology
While uncommon, CNS-IRIS developing after the initiation of HAART in the setting of HIV-
related severe immunosuppression is characterized by an intense inflammatory reaction to …

White matter damage and systemic inflammation in obstructive sleep apnea

HL Chen, CH Lu, HC Lin, PC Chen, KH Chou, WM Lin… - Sleep, 2015 - academic.oup.com
Abstract Study Objectives: To evaluate white matter integrity in patients with obstructive
sleep apnea (OSA) using diffusion tensor imaging (DTI) and to assess its relationship with …

[HTML][HTML] Neuroimaging of cryptococcal meningitis in patients without human immunodeficiency virus: data from a multi-center cohort study

SH Anjum, JE Bennett, O Dean, KA Marr… - Journal of Fungi, 2023 - mdpi.com
Background: A clearer understanding is needed about the use of brain MRI in non-HIV
patients with cryptococcal meningitis. Methods: Cerebral CT and MRI were studied in 62 …

Predictors of neurocognitive outcomes on antiretroviral therapy after cryptococcal meningitis: a prospective cohort study

RD Carlson, MA Rolfes, KE Birkenkamp… - Metabolic brain …, 2014 - Springer
Cryptococcal meningitis is the most common cause of adult meningitis in Africa, yet
neurocognitive outcomes are unknown. We investigated the incidence and predictors of …

Gray and white matter alterations in early HIV‐infected patients: Combined voxel‐based morphometry and tract‐based spatial statistics

B Wang, Z Liu, J Liu, Z Tang, H Li… - Journal of Magnetic …, 2016 - Wiley Online Library
Purpose To investigate both the gray matter (GM) and whiter matter (WM) alterations in a
homogeneous cohort of early HIV‐infected patients by combining voxel‐based morphometry …

[HTML][HTML] White matter abnormalities correlating with memory and depression in heroin users under methadone maintenance treatment

WC Lin, KH Chou, CC Chen, CC Huang, HL Chen… - PLoS …, 2012 - journals.plos.org
Methadone maintenance treatment (MMT) has elevated rates of co-morbid memory deficit
and depression that are associated with higher relapse rates for substance abuse. White …

An Antivirulence approach for preventing Cryptococcus neoformans from crossing the blood-brain barrier via novel natural product inhibitors of a fungal …

PA Aaron, K Vu, A Gelli - MBio, 2020 - Am Soc Microbiol
Cryptococcus neoformans (Cn) is the leading cause of fungal meningitis, a deadly disease
with limited therapeutic options. Dissemination to the central nervous system hinges on the …

[HTML][HTML] HIV-negative cryptococcal meningoencephalitis results in a persistent frontal-subcortical syndrome

K Traino, J Snow, L Ham, A Summers, L Segalà… - Scientific reports, 2019 - nature.com
Twenty-seven previously healthy (of 36 consecutive eligible patients), HIV-negative
cryptococcal meningoencephalitis (CM) patients underwent comprehensive …

[HTML][HTML] Connectivity of default-mode network is associated with cerebral edema in hepatic encephalopathy

WC Lin, TW Hsu, CL Chen, CW Wu, CH Lu, HL Chen… - PLoS …, 2012 - journals.plos.org
Cerebral edema, a well-known feature of acute liver disease, can occur in cirrhotic patients
regardless of hepatic encephalopathy (HE) and adversely affect prognosis. This study …