Brain fluorodeoxyglucose (FDG) PET in dementia

T Kato, Y Inui, A Nakamura, K Ito - Ageing research reviews, 2016 - Elsevier
The purpose of this article is to present a selective and concise summary of
fluorodeoxyglucose (FDG) positron emission tomography (PET) in dementia imaging. FDG …

[HTML][HTML] Blood–brain barrier opening in Alzheimer's disease using MR-guided focused ultrasound

N Lipsman, Y Meng, AJ Bethune, Y Huang… - Nature …, 2018 - nature.com
Magnetic resonance-guided focused ultrasound in combination with intravenously injected
microbubbles has been shown to transiently open the blood–brain barrier, and reduce beta …

PET approaches for diagnosis of dementia

K Ishii - American Journal of Neuroradiology, 2014 - Am Soc Neuroradiology
There is increasing use of neuroimaging modalities, including PET, for diagnosing
dementia. For example, FDG-PET demonstrates hypometabolic regions in the posterior …

[HTML][HTML] The effect of chronic cerebral hypoperfusion on the pathology of Alzheimer's disease: a positron emission tomography study in rats

JH Park, JH Hong, SW Lee, HD Ji, JA Jung, KW Yoon… - Scientific reports, 2019 - nature.com
Cerebrovascular disease is a potential risk factor for Alzheimer's disease (AD). Although
acute cerebral hypoperfusion causes neuronal necrosis and infarction, chronic cerebral …

In vivo mitochondrial and glycolytic impairments in patients with Alzheimer disease

T Terada, T Obi, T Bunai, T Matsudaira, E Yoshikawa… - Neurology, 2020 - AAN Enterprises
Objective In vivo glycolysis-related glucose metabolism and electron transport chain-related
mitochondrial activity may be different regionally in the brains of patients with Alzheimer …

Diagnostic classification of arterial spin labeling and structural MRI in presenile early stage dementia

EE Bron, RME Steketee, GC Houston… - Human brain …, 2014 - Wiley Online Library
Because hypoperfusion of brain tissue precedes atrophy in dementia, the detection of
dementia may be advanced by the use of perfusion information. Such information can be …

Clinical validity of brain fluorodeoxyglucose positron emission tomography as a biomarker for Alzheimer's disease in the context of a structured 5-phase development …

V Garibotto, K Herholz, M Boccardi, A Picco… - Neurobiology of …, 2017 - Elsevier
The use of Alzheimer's disease (AD) biomarkers is supported in diagnostic criteria, but their
maturity for clinical routine is still debated. Here, we evaluate brain fluorodeoxyglucose …

Regional correlation between resting state FDG PET and pCASL perfusion MRI

YHK Cha, MA Jog, YC Kim… - Journal of Cerebral …, 2013 - journals.sagepub.com
To determine how arterial spin labeling (ASL) measured perfusion relates to baseline
metabolism, we compared resting state cerebral perfusion using pseudo-continuous ASL …

[HTML][HTML] Regional uptakes from early-frame amyloid PET and 18F-FDG PET scans are comparable independent of disease state

A Myoraku, G Klein, S Landau, D Tosun… - European Journal of …, 2022 - Springer
Purpose Positron emission tomography (PET) imaging with amyloid-beta (Aβ) tracers and 2-
[18F] fluoro-2-Deoxy-d-glucose (18F-FDG) is extensively employed in Alzheimer's disease …

Application of the National Institute on Aging-Alzheimer's Association AD criteria to ADNI

VJ Lowe, PJ Peller, SD Weigand, C Montoya Quintero… - Neurology, 2013 - AAN Enterprises
Objective: We describe the operationalization of the National Institute on Aging-Alzheimer's
Association (NIA-AA) workgroup diagnostic guidelines pertaining to Alzheimer disease (AD) …