High WSS or low WSS? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture: toward a unifying hypothesis

H Meng, VM Tutino, J Xiang… - American Journal of …, 2014 - Am Soc Neuroradiology
Increasing detection of unruptured intracranial aneurysms, catastrophic outcomes from
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …

Mechanism of action and biology of flow diverters in the treatment of intracranial aneurysms

K Ravindran, AM Casabella, J Cebral, W Brinjikji… - …, 2020 - journals.lww.com
Flow diverters have drastically changed the landscape of intracranial aneurysm treatment
and are now considered first-line therapy for select lesions. Their mechanism of action relies …

Flow conditions in the intracranial aneurysm lumen are associated with inflammation and degenerative changes of the aneurysm wall

J Cebral, E Ollikainen, BJ Chung… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Saccular intracranial aneurysm is a common disease that
may cause devastating intracranial hemorrhage. Hemodynamics, wall remodeling, and wall …

[HTML][HTML] Heart blood flow simulation: a perspective review

SN Doost, D Ghista, B Su, L Zhong… - Biomedical engineering …, 2016 - Springer
Cardiovascular disease (CVD), the leading cause of death today, incorporates a wide range
of cardiovascular system malfunctions that affect heart functionality. It is believed that the …

CFD: computational fluid dynamics or confounding factor dissemination? The role of hemodynamics in intracranial aneurysm rupture risk assessment

J Xiang, VM Tutino, KV Snyder… - American Journal of …, 2014 - Am Soc Neuroradiology
Image-based computational fluid dynamics holds a prominent position in the evaluation of
intracranial aneurysms, especially as a promising tool to stratify rupture risk. Current …

Mind the gap: impact of computational fluid dynamics solution strategy on prediction of intracranial aneurysm hemodynamics and rupture status indicators

K Valen-Sendstad… - American Journal of …, 2014 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Computational fluid dynamics has become a popular tool
for studying intracranial aneurysm hemodynamics, demonstrating success for retrospectively …

CFD for evaluation and treatment planning of aneurysms: review of proposed clinical uses and their challenges

B Chung, JR Cebral - Annals of biomedical engineering, 2015 - Springer
Computational fluid dynamics (CFD) has been used for several years to identify mechanical
risk factors associated with aneurysmal evolution and rupture as well as to understand flow …

[HTML][HTML] Reinforcement learning for patient-specific optimal stenting of intracranial aneurysms

E Hachem, P Meliga, A Goetz, PJ Rico, J Viquerat… - Scientific Reports, 2023 - nature.com
Developing new capabilities to predict the risk of intracranial aneurysm rupture and to
improve treatment outcomes in the follow-up of endovascular repair is of tremendous …

Variability of computational fluid dynamics solutions for pressure and flow in a giant aneurysm: the ASME 2012 Summer Bioengineering Conference CFD Challenge

DA Steinman, Y Hoi, P Fahy… - Journal of …, 2013 - asmedigitalcollection.asme.org
Stimulated by a recent controversy regarding pressure drops predicted in a giant aneurysm
with a proximal stenosis, the present study sought to assess variability in the prediction of …

Multiple aneurysms anatomy challenge 2018 (MATCH): phase I: segmentation

P Berg, S Voß, S Saalfeld, G Janiga… - Cardiovascular …, 2018 - Springer
Purpose Advanced morphology analysis and image-based hemodynamic simulations are
increasingly used to assess the rupture risk of intracranial aneurysms (IAs). However, the …