[HTML][HTML] Systematic review: quantitative susceptibility mapping (QSM) of brain iron profile in neurodegenerative diseases

P Ravanfar, SM Loi, WT Syeda… - Frontiers in …, 2021 - frontiersin.org
Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In
the past decade, development of the new magnetic resonance imaging technique …

[HTML][HTML] Cerebral iron deposition in neurodegeneration

P Dusek, T Hofer, J Alexander, PM Roos, JO Aaseth - Biomolecules, 2022 - mdpi.com
Disruption of cerebral iron regulation appears to have a role in aging and in the
pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron …

[HTML][HTML] Novel insights into ferroptosis: Implications for age-related diseases

RP Zhou, Y Chen, X Wei, B Yu, ZG Xiong, C Lu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rapid increase in aging populations is an urgent problem because older adults are more
likely to suffer from disabilities and age-related diseases (ARDs), burdening healthcare …

No effects without causes: the Iron Dysregulation and Dormant Microbes hypothesis for chronic, inflammatory diseases

DB Kell, E Pretorius - Biological Reviews, 2018 - Wiley Online Library
Since the successful conquest of many acute, communicable (infectious) diseases through
the use of vaccines and antibiotics, the currently most prevalent diseases are chronic and …

[HTML][HTML] Anti-inflammatory and neuroprotective agents in clinical trials for CNS disease and injury: where do we go from here?

K Mallah, C Couch, DM Borucki, A Toutonji… - Frontiers in …, 2020 - frontiersin.org
Neurological disorders are major contributors to death and disability worldwide. The
pathology of injuries and disease processes includes a cascade of events that often involve …

Quantitative susceptibility mapping: technical considerations and clinical applications in neuroimaging

S Vinayagamani, R Sheelakumari… - Journal of Magnetic …, 2021 - Wiley Online Library
Quantitative susceptibility mapping (QSM) is a novel magnetic resonance imaging (MRI)
technique for quantifying the spatial distribution of magnetic susceptibility within an object or …

[HTML][HTML] Crosstalk between the gut microbiota and the brain: an update on neuroimaging findings

P Liu, G Peng, N Zhang, B Wang, B Luo - Frontiers in neurology, 2019 - frontiersin.org
An increasing amount of evidence suggests that bidirectional communication between the
gut microbiome and the central nervous system (CNS), which is also known as the …

[HTML][HTML] Imaging biomarkers for the diagnosis and prognosis of neurodegenerative diseases. The example of amyotrophic lateral sclerosis

M Mazón, JF Vázquez Costa, A Ten-Esteve… - Frontiers in …, 2018 - frontiersin.org
The term amyotrophic lateral sclerosis (ALS) comprises a heterogeneous group of fatal
neurodegenerative disorders of largely unknown etiology characterized by the upper motor …

Iron quantitative analysis of motor combined with bulbar region in M1 cortex may improve diagnosis performance in ALS

Y Bao, Y Chen, S Piao, B Hu, L Yang, H Li, D Geng… - European …, 2023 - Springer
Objectives To explore whether the combined analysis of motor and bulbar region of M1 on
susceptibility-weighted imaging (SWI) can be a valid biomarker for amyotrophic lateral …

[HTML][HTML] Characterization of brain iron deposition pattern and its association with genetic risk factor in Alzheimer's disease using susceptibility-weighted imaging

P You, X Li, Z Wang, H Wang, B Dong… - Frontiers in Human …, 2021 - frontiersin.org
The presence of iron is an important factor for normal brain functions, whereas excessive
deposition of iron may impair normal cognitive function in the brain and lead to Alzheimer's …