2021 WHO classification of tumours of the central nervous system: a review for the neuroradiologist
The fifth edition of the World Health Organization Classification of Tumours of the Central
Nervous System (WHO CNS5) published in 2021 builds on the 2016 edition and …
Nervous System (WHO CNS5) published in 2021 builds on the 2016 edition and …
[HTML][HTML] Imaging features associated with H3 K27-altered and H3 G34-mutant gliomas: a narrative systematic review
A Lasocki, G Abdalla, G Chow, SC Thust - Cancer Imaging, 2022 - Springer
Background Advances in molecular diagnostics accomplished the discovery of two
malignant glioma entities harboring alterations in the H3 histone: diffuse midline glioma, H3 …
malignant glioma entities harboring alterations in the H3 histone: diffuse midline glioma, H3 …
[HTML][HTML] Diffuse midline gliomas with histone H3 K27M mutation in adults and children: a retrospective series of 164 cases
L Zheng, J Gong, T Yu, Y Zou, M Zhang… - The American Journal …, 2022 - journals.lww.com
Diffuse midline glioma, H3 K27M-mutant (H3 K27M-mt DMG), is a rare and highly
aggressive tumor that is more common in children than in adults. Few studies have …
aggressive tumor that is more common in children than in adults. Few studies have …
MR imaging features of diffuse intrinsic pontine glioma and relationship to overall survival: report from the International DIPG Registry
JL Leach, J Roebker, A Schafer, J Baugh… - Neuro …, 2020 - academic.oup.com
Background This study describes imaging features of diffuse intrinsic pontine glioma (DIPG)
and correlates with overall survival (OS) and histone mutation status in the International …
and correlates with overall survival (OS) and histone mutation status in the International …
[HTML][HTML] Advanced magnetic resonance imaging in pediatric glioblastomas
FG Gonçalves, AN Viaene, A Vossough - Frontiers in Neurology, 2021 - frontiersin.org
The shortly upcoming 5th edition of the World Health Organization Classification of Tumors
of the Central Nervous System is bringing extensive changes in the terminology of diffuse …
of the Central Nervous System is bringing extensive changes in the terminology of diffuse …
MRI-based radiomics signature and clinical factor for predicting H3K27M mutation in pediatric high-grade gliomas located in the midline of the brain
C Wu, H Zheng, J Li, Y Zhang, S Duan, Y Li… - European Radiology, 2022 - Springer
Objective To develop a nomogram based on MRI radiomics and clinical features for
preoperatively predicting H3K27M mutation in pediatric high-grade gliomas (pHGGs) with a …
preoperatively predicting H3K27M mutation in pediatric high-grade gliomas (pHGGs) with a …
Dynamic susceptibility contrast-MRI parameters, ADC values, and the T2-FLAIR mismatch sign are useful to differentiate between H3-mutant and H3-wild-type high …
Objectives Diffuse midline gliomas, H3K27-altered (DMG-A), are malignant gliomas with an
unfavorable prognosis. Knowledge of dynamic susceptibility contrast (DSC) MRI findings …
unfavorable prognosis. Knowledge of dynamic susceptibility contrast (DSC) MRI findings …
Machine learning-based multiparametric magnetic resonance imaging radiomics for prediction of H3K27M mutation in midline gliomas
Objective H3K27M mutation in gliomas has prognostic implications. Previous magnetic
resonance imaging (MRI) studies have reported variable rates of tumoral enhancement …
resonance imaging (MRI) studies have reported variable rates of tumoral enhancement …
[HTML][HTML] Imaging diagnosis and treatment selection for brain tumors in the era of molecular therapeutics
Currently, most CNS tumors require tissue sampling to discern their molecular/genomic
landscape. However, growing research has shown the powerful role imaging can play in …
landscape. However, growing research has shown the powerful role imaging can play in …
[HTML][HTML] Adult-type and pediatric-type diffuse gliomas: What the neuroradiologist should know
R Nafe, L Porto, PF Samp, SJ You, E Hattingen - Clinical Neuroradiology, 2023 - Springer
The classification of diffuse gliomas into the adult type and the pediatric type is the new
basis for the diagnosis and clinical evaluation. The knowledge for the neuroradiologist …
basis for the diagnosis and clinical evaluation. The knowledge for the neuroradiologist …