Current concepts in intracranial interstitial fluid transport and the glymphatic system: part II—imaging techniques and clinical applications

JM Klostranec, D Vucevic, KD Bhatia, HGJ Kortman… - Radiology, 2021 - pubs.rsna.org
The glymphatic system is a recently discovered network unique to the central nervous
system that allows for dynamic exchange of interstitial fluid (ISF) and cerebrospinal fluid …

Contrast‐Enhanced Fluid‐Attenuated Inversion Recovery in Neuroimaging: A Narrative Review on Clinical Applications and Technical Advances

SJ Ahn, T Taoka, WJ Moon… - Journal of Magnetic …, 2022 - Wiley Online Library
While contrast‐enhanced fluid‐attenuated inversion recovery (FLAIR) has long been
regarded as an adjunct sequence to evaluate leptomeningeal disease in addition to contrast …

Noninvasive characterization of human glymphatics and meningeal lymphatics in an in vivo model of blood–brain barrier leakage

CH Wu, JF Lirng, YH Ling, YF Wang, HM Wu… - Annals of …, 2021 - Wiley Online Library
Objective To evaluate human glymphatics and meningeal lymphatics noninvasively.
Methods This prospective study implemented 3‐dimensional (3D) isotropic contrast …

Confirmation of age-dependence in the leakage of contrast medium around the cortical veins into cerebrospinal fluid after intravenous administration of gadolinium …

S Naganawa, R Ito, H Kawai, T Taoka… - … Resonance in Medical …, 2020 - jstage.jst.go.jp
Purpose: It has been reported previously that intravenously administered gadolinium-based
contrast agent (GBCA) leaks into the subarachnoid space around the cortical veins at 4 h …

[HTML][HTML] Application of contrast-enhanced magnetic resonance imaging in the assessment of blood-cerebrospinal fluid barrier integrity

ICM Verheggen, WM Freeze, JJA de Jong… - Neuroscience & …, 2021 - Elsevier
Abstract VERHEGGEN, ICM, W. Freeze, J. de Jong, J. Jansen, A. Postma, M. van Boxtel, F.
Verhey and W. Backes. The application of contrast-enhanced MRI in the assessment of …

Blood-brain barrier permeability in patients with reversible cerebral vasoconstriction syndrome assessed with dynamic contrast-enhanced MRI

CH Wu, JF Lirng, HM Wu, YH Ling, YF Wang, JL Fuh… - Neurology, 2021 - AAN Enterprises
Background and Objectives Blood-brain barrier (BBB) disruption has been proposed to be
important in the pathogenesis of reversible cerebral vasoconstriction syndrome (RCVS), but …

[HTML][HTML] CSF enhancement on post-contrast fluid-attenuated inversion recovery images; a systematic review

WM Freeze, M van der Thiel, J de Bresser, CJM Klijn… - NeuroImage: Clinical, 2020 - Elsevier
Cerebrospinal fluid (CSF) enhancement on T2-weighted post-contrast fluid-attenuated
inversion recovery (pcT2wFLAIR) images is a relatively unknown neuroradiological marker …

Optimal sequences and sequence parameters for GBCA-enhanced MRI of the glymphatic system: a systematic literature review

LSP Mijnders, FWR Steup, M Lindhout… - Acta …, 2021 - journals.sagepub.com
Background The glymphatic system (GS) is a recently discovered waste clearance system in
the brain. Purpose To evaluate the most promising magnetic resonance imaging (MRI) …

Spectrum and Mimics of Brain Surface Enhancement on Postcontrast FLAIR Images

SN Rogers, JL Becker - Neurographics, 2023 - ingentaconnect.com
Brain surface enhancement on FLAIR describes increased FLAIR signal at the brain surface
after the administration of gadolinium-based contrast agents. Because of the unique …

Gadolinium-based imaging of the blood brain barrier and brain waste clearance pathways

N Agarwal, DM Harrison - Advances in Magnetic Resonance Technology …, 2023 - Elsevier
The recent demonstration of brain waste clearance pathways, including the presence of
meningeal lymphatics, is fundamental in our understanding of neuroinflammatory and …