Currently, over five million Americans suffer with Alzheimer's disease (AD). In the absence of
a cure, this number could increase to 13.8 million by 2050. A critical goal of biomedical …

Alzheimer's disease (AD) has traditionally been regarded as a disease of the gray matter
(GM). However, the advent of diffusion tensor imaging (DTI) has contributed to new …

Cerebral white matter lesions (WML) encompass axonal loss and demyelination, and the
pathogenesis is assumed to be small vessel disease (SVD)-related ischemia. However …

Recent imaging evidence in Alzheimer's disease suggests that neural involvement in early-
stage disease is more complex than is encapsulated in the commonly held position of …

In early Alzheimer's disease (AD), the hippocampal region is the area most severely affected
by cellular and structural alterations, yet glucose hypometabolism predominates in the …

Purpose To explore the regional patterns of white matter (WM) tract damage in (a) patients
with probable Alzheimer disease (AD) and (b) patients with amnestic mild cognitive …

Frontotemporal dementia (FTD) and Alzheimer's disease are sometimes difficult to
differentiate clinically because of overlapping symptoms. Using diffusion tensor imaging …

White matter (WM) damage has been reported in Alzheimer's Disease (AD) and Mild
Cognitive Impairment (MCI) in diffusion tensor imaging (DTI) studies. It is, however, unknown …

A subgroup of patients with breast cancer suffers from mild cognitive impairment after
chemotherapy. To uncover the neural substrate of these mental complaints, we examined …

Atrophy of the medial temporal lobe, especially the hippocampus and the parahippocampal
gyrus, is considered to be the most predictive structural brain biomarker for Alzheimer's …