Magnetic resonance imaging of the subthalamic nucleus for deep brain stimulation

AS Chandran, M Bynevelt, CRP Lind - Journal of neurosurgery, 2016 - thejns.org
The subthalamic nucleus (STN) is one of the most important stereotactic targets in
neurosurgery, and its accurate imaging is crucial. With improving MRI sequences there is …

Toward in vivo histology: a comparison of quantitative susceptibility mapping (QSM) with magnitude-, phase-, and R2⁎-imaging at ultra-high magnetic field strength

A Deistung, A Schäfer, F Schweser, U Biedermann… - Neuroimage, 2013 - Elsevier
Quantitative magnetic susceptibility mapping (QSM) has recently been introduced to provide
a novel quantitative and local MRI contrast. However, the anatomical contrast represented …

Iron deposition quantification: applications in the brain and liver

F Yan, N He, H Lin, R Li - Journal of Magnetic Resonance …, 2018 - Wiley Online Library
Iron has long been implicated in many neurological and other organ diseases. It is known
that over and above the normal increases in iron with age, in certain diseases there is an …

An assessment of current brain targets for deep brain stimulation surgery with susceptibility-weighted imaging at 7 tesla

A Abosch, E Yacoub, K Ugurbil, N Harel - Neurosurgery, 2010 - journals.lww.com
BACKGROUND: Deep brain stimulation (DBS) surgery is used for treating movement
disorders, including Parkinson disease, essential tremor, and dystonia. Successful DBS …

Seven‐Tesla magnetic resonance images of the substantia nigra in Parkinson disease

DH Kwon, JM Kim, SH Oh, HJ Jeong… - Annals of …, 2012 - Wiley Online Library
Objective: To investigate anatomical changes in the substantia nigra (SN) of Parkinson
disease (PD) patients with age‐matched controls by using ultra‐high field magnetic …

[BOOK][B] Susceptibility weighted imaging in MRI: basic concepts and clinical applications

EM Haacke, JR Reichenbach - 2014 - books.google.com
MRI Susceptibility Weighted Imaging discusses the promising new MRI technique called
Susceptibility Weighted Imaging (SWI), a powerful tool for the diagnosis and treatment of …

MRI estimates of brain iron concentration in normal aging: comparison of field-dependent (FDRI) and phase (SWI) methods

A Pfefferbaum, E Adalsteinsson, T Rohlfing… - Neuroimage, 2009 - Elsevier
Different brain structures accumulate iron at different rates throughout the adult life span.
Typically, striatal and brain stem structures are higher in iron concentrations in older than …

[HTML][HTML] Comparison of T2*-weighted and QSM contrasts in Parkinson's disease to visualize the STN with MRI

A Alkemade, G de Hollander, MC Keuken, A Schäfer… - PloS one, 2017 - journals.plos.org
The subthalamic nucleus (STN) plays a crucial role in the surgical treatment of Parkinson's
disease (PD). Studies investigating optimal protocols for STN visualization using state of the …

Imaging nigral pathology and clinical progression in Parkinson's disease

G Du, MM Lewis, S Sen, J Wang, ML Shaffer… - Movement …, 2012 - Wiley Online Library
The pattern of dopamine cell loss in Parkinson's disease (PD) is known to be prominent in
the ventrolateral and caudal substantia nigra (SN), but less severe in the dorsal and rostral …

[HTML][HTML] Feasibility of using ultra-high field (7 T) MRI for clinical surgical targeting

Y Duchin, A Abosch, E Yacoub, G Sapiro, N Harel - PloS one, 2012 - journals.plos.org
The advantages of ultra-high magnetic field (7 Tesla) MRI for basic science research and
neuroscience applications have proven invaluable. Structural and functional MR images of …