Grey matter lesions in MS: from histology to clinical implications

M Calabrese, A Favaretto, V Martini, P Gallo - Prion, 2013 - Taylor & Francis
Although multiple sclerosis (MS) is a chronic inflammatory-demyelinating disease of the
white matter (WM) of the central nervous system, several pathological and magnetic …

[HTML][HTML] Cognitive issues in pediatric multiple sclerosis

E Portaccio, E De Meo, A Bellinvia, MP Amato - Brain Sciences, 2021 - mdpi.com
Multiple sclerosis (MS) is one of the leading causes of disability in young adults. The onset
of MS during developmental age makes pediatric patients particularly susceptible to …

Common comorbid and secondary conditions leading to hospitalization in multiple sclerosis patients in the United States

AO Asemota, EB Schneider, EM Mowry… - Clinical Neurology and …, 2023 - Elsevier
Objective To identify the burden of hospitalization and common primary admitting diagnoses
among MS patients in the United States (US). Background The burden of hospitalizations …

Can optical coherence tomography be used to guide treatment decisions in adult or pediatric multiple sclerosis?

J Lambe, OC Murphy, S Saidha - Current Treatment Options in Neurology, 2018 - Springer
Purpose of review With the recognition that neurodegeneration represents the principal
substrate of disability in multiple sclerosis (MS), there has been increased strives towards …

Leptomeningeal contrast enhancement is related to focal cortical thinning in relapsing-remitting multiple sclerosis: A cross-sectional MRI study

N Bergsland, D Ramasamy, E Tavazzi… - American Journal …, 2019 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Leptomeningeal inflammation is associated with the
development of global cortical gray matter atrophy in multiple sclerosis. However, its …

Pediatric multiple sclerosis: developments in timely diagnosis and prognostication

M Margoni, P Preziosa, MA Rocca… - Expert Review of …, 2022 - Taylor & Francis
Introduction Pediatric-onset (PO) multiple sclerosis (MS) accounts for about 2–10% of the
total MS cases. Recently, a greater attention has been given to POMS, with substantial …

[HTML][HTML] Gray matter pathology in MS: neuroimaging and clinical correlations

JM Honce - Multiple sclerosis international, 2013 - hindawi.com
It is abundantly clear that there is extensive gray matter pathology occurring in multiple
sclerosis. While attention to gray matter pathology was initially limited to studies of autopsy …

[HTML][HTML] Whole brain and deep gray matter atrophy detection over 5 years with 3T MRI in multiple sclerosis using a variety of automated segmentation pipelines

R Chu, G Kim, S Tauhid, F Khalid, BC Healy… - PLoS One, 2018 - journals.plos.org
Background Cerebral atrophy is common in multiple sclerosis (MS) and selectively involves
gray matter (GM). Several fully automated methods are available to measure whole brain …

7T MRI visualization of cortical lesions in adolescents and young adults with pediatric‐onset multiple sclerosis

R Datta, V Sethi, S Ly, AT Waldman… - Journal of …, 2017 - Wiley Online Library
ABSTRACT BACKGROUND Cortical pathology in multiple sclerosis (MS) has been
associated with prolonged and progressive disease. 7T magnetic resonance imaging (MRI) …

Detection and clinical correlation of leukocortical lesions in pediatric-onset multiple sclerosis on multi-contrast MRI

J Maranzano, C Till, HE Assemlal… - Multiple Sclerosis …, 2019 - journals.sagepub.com
Objective: To determine the frequency of cortical lesions (CLs) in patients with pediatric-
onset multiple sclerosis (POMS) using multi-contrast magnetic resonance imaging (MRI) …