The thalamus and multiple sclerosis: modern views on pathologic, imaging, and clinical aspects

A Minagar, MH Barnett, RHB Benedict, D Pelletier… - Neurology, 2013 - AAN Enterprises
The paired thalamic nuclei are gray matter (GM) structures on both sides of the third ventricle
that play major roles in cortical activation, relaying sensory information to the higher cortical …

An illustrated comparison of processing methods for MR phase imaging and QSM: combining array coil signals and phase unwrapping

SD Robinson, K Bredies, D Khabipova… - NMR in …, 2017 - Wiley Online Library
Phase imaging benefits from strong susceptibility effects at very high field and the high
signal‐to‐noise ratio (SNR) afforded by multi‐channel coils. Combining the information from …

Quantitative susceptibility mapping in multiple sclerosis

C Langkammer, T Liu, M Khalil, C Enzinger, M Jehna… - Radiology, 2013 - pubs.rsna.org
Purpose To apply quantitative susceptibility mapping (QSM) in the basal ganglia of patients
with multiple sclerosis (MS) and relate the findings to R2* mapping with regard to the …

[HTML][HTML] Thalamic injury and cognition in multiple sclerosis

M Amin, D Ontaneda - Frontiers in Neurology, 2021 - frontiersin.org
Multiple sclerosis (MS) produces demyelination and degeneration in both gray and white
matter. Both cortical and deep gray matter injury is observed during the course of MS …

[HTML][HTML] Iron and multiple sclerosis

JM Stankiewicz, M Neema, A Ceccarelli - Neurobiology of aging, 2014 - Elsevier
Iron is essential for normal cellular functioning of the central nervous system. Abnormalities
in iron metabolism may lead to neuronal death and abnormal iron deposition in the brain …

Mapping of thalamic magnetic susceptibility in multiple sclerosis indicates decreasing iron with disease duration: a proposed mechanistic relationship between …

F Schweser, ALRD Martins, J Hagemeier, F Lin… - Neuroimage, 2018 - Elsevier
Recent advances in susceptibility MRI have dramatically improved the visualization of deep
gray matter brain regions and the quantification of their magnetic properties in vivo …

Brain iron accumulation in aging and neurodegenerative disorders

J Hagemeier, JJG Geurts… - Expert review of …, 2012 - Taylor & Francis
Over the decades, various studies have established an association between accumulation
of iron and both aging and neurodegenerative disorders such as Alzheimer's disease and …

[HTML][HTML] Gray matters in multiple sclerosis: cognitive impairment and structural MRI

S Messina, F Patti - Multiple sclerosis international, 2014 - hindawi.com
Multiple sclerosis (MS) is an immune-mediated disease affecting central nervous system
(CNS). Although MS is classically considered a white matter (WM) disease, the involvement …

Neuroradiological evaluation of demyelinating disease

JM Tillema, I Pirko - Therapeutic advances in neurological …, 2013 - journals.sagepub.com
Central nervous system inflammatory demyelinating disease can affect patients across the
life span. Consensus definitions and criteria of all of the different acquired demyelinating …

Hippocampal microstructural damage correlates with memory impairment in clinically isolated syndrome suggestive of multiple sclerosis

V Planche, A Ruet, P Coupé… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Objective: We investigated whether diffusion tensor imaging (DTI) could reveal early
hippocampal damage and clinically relevant correlates of memory impairment in persons …