Cerebrospinal fluid mechanics and its coupling to cerebrovascular dynamics

AA Linninger, K Tangen, CY Hsu… - Annual Review of Fluid …, 2016 - annualreviews.org
Cerebrospinal fluid (CSF) is not stagnant but displays fascinating oscillatory flow patterns
inside the ventricular system and reversing fluid exchange between the cranial vault and …

Spinal fluid biomechanics and imaging: an update for neuroradiologists

V Haughton, KA Mardal - American Journal of …, 2014 - Am Soc Neuroradiology
Flow imaging with cardiac-gated phase-contrast MR has applications in the management of
neurologic disorders. Together with computational fluid dynamics, phase-contrast MR has …

[HTML][HTML] Respiratory influence on cerebrospinal fluid flow–a computational study based on long-term intracranial pressure measurements

V Vinje, G Ringstad, EK Lindstrøm, LM Valnes… - Scientific reports, 2019 - nature.com
Current theories suggest that waste solutes are cleared from the brain via cerebrospinal fluid
(CSF) flow, driven by pressure pulsations of possibly both cardiac and respiratory origin. In …

CNS wide simulation of flow resistance and drug transport due to spinal microanatomy

KM Tangen, Y Hsu, DC Zhu, AA Linninger - Journal of biomechanics, 2015 - Elsevier
Spinal microstructures are known to substantially affect cerebrospinal fluid patterns, yet their
actual impact on flow resistance has not been quantified. Because the length scale of …

[HTML][HTML] Hydraulic resistance of periarterial spaces in the brain

J Tithof, DH Kelley, H Mestre, M Nedergaard… - Fluids and Barriers of …, 2019 - Springer
Abstract Background Periarterial spaces (PASs) are annular channels that surround arteries
in the brain and contain cerebrospinal fluid (CSF): a flow of CSF in these channels is thought …

[HTML][HTML] Comparison of 4D phase-contrast MRI flow measurements to computational fluid dynamics simulations of cerebrospinal fluid motion in the cervical spine

TI Yiallourou, JR Kröger, N Stergiopulos, D Maintz… - PloS one, 2012 - journals.plos.org
Cerebrospinal fluid (CSF) dynamics in the cervical spinal subarachnoid space (SSS) have
been thought to be important to help diagnose and assess craniospinal disorders such as …

Rotating stall observations in a high speed compressor—Part I: Experimental study

J Dodds, M Vahdati - Journal of Turbomachinery, 2015 - asmedigitalcollection.asme.org
In this two-part paper, the phenomenon of part span rotating stall is studied. The objective is
to improve understanding of the physics by which stable and persistent rotating stall occurs …

[HTML][HTML] In vitro evaluation of cerebrospinal fluid velocity measurement in type I Chiari malformation: repeatability, reproducibility, and agreement using 2D phase …

G Williams, S Thyagaraj, A Fu, J Oshinski… - Fluids and Barriers of …, 2021 - Springer
Background Phase contrast magnetic resonance imaging, PC MRI, is a valuable tool
allowing for non-invasive quantification of CSF dynamics, but has lacked adoption in clinical …

[HTML][HTML] Correlation of a new hydrodynamic index with other effective indexes in Chiari I malformation patients with different associations

S Gholampour, H Gholampour - Scientific Reports, 2020 - nature.com
This study aimed to find a new CSF hydrodynamic index to assess Chiari type I malformation
(CM-I) patients' conditions and examine the relationship of this new index with morphometric …

Anthropomorphic model of intrathecal cerebrospinal fluid dynamics within the spinal subarachnoid space: spinal cord nerve roots increase steady-streaming

M Khani, LR Sass, T Xing… - Journal of …, 2018 - asmedigitalcollection.asme.org
Cerebrospinal fluid (CSF) dynamics are thought to play a vital role in central nervous system
(CNS) physiology. The objective of this study was to investigate the impact of spinal cord …