Malformations of cortical development and epilepsy

AJ Barkovich, WB Dobyns… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Malformations of cortical development (MCDs) are an important cause of epilepsy and an
extremely interesting group of disorders from the perspective of brain development and its …

[HTML][HTML] Corpus callosum and epilepsies

I Unterberger, R Bauer, G Walser, G Bauer - Seizure, 2016 - Elsevier
Purpose Corpus callosum (CC) is the largest forebrain commissure. This review focuses on
the significance of CC for seizure disorders, the role of CC in seizure spread and the …

[HTML][HTML] 47 patients with FLNA associated periventricular nodular heterotopia

M Lange, B Kasper, A Bohring, F Rutsch… - Orphanet journal of rare …, 2015 - Springer
Background Heterozygous loss of function mutations within the Filamin A gene in Xq28 are
the most frequent cause of bilateral neuronal periventricular nodular heterotopia (PVNH) …

Whole-brain multimodal MRI phenotyping of periventricular nodular heterotopia

F Deleo, SJ Hong, F Fadaie, B Caldairou, S Krystal… - Neurology, 2020 - AAN Enterprises
Objective To test the hypothesis that in periventricular nodular heterotopia (PVNH) structure
and function of cortical areas overlying the heterotopic gray matter are preferentially …

Functional connectivity and epileptogenicity of nodular heterotopias: A single‐pulse stimulation study

S Boulogne, F Pizzo, B Chatard, N Roehri… - …, 2022 - Wiley Online Library
Abstract Objective Nodular heterotopias (NHs) are malformations of cortical development
associated with drug‐resistant focal epilepsy with frequent poor surgical outcome. The …

Fetal magnetic resonance imaging: supratentorial brain malformations

JJ Choi, E Yang, JS Soul, C Jaimes - Pediatric Radiology, 2020 - Springer
Fetal MRI is the modality of choice to study supratentorial brain malformations. To accurately
interpret the MRI, the radiologist needs to understand the normal sequence of events that …

X‐linked neuronal migration disorders: Gender differences and insights for genetic screening

J Edey, P Soleimani‐Nouri… - International Journal …, 2023 - Wiley Online Library
Cortical development depends on neuronal migration of both excitatory and inhibitory
interneurons. Neuronal migration disorders (NMDs) are conditions characterised by …

[HTML][HTML] Germline and somatic mutations in cortical malformations: molecular defects in Argentinean patients with neuronal migration disorders

D González-Morón, S Vishnopolska, D Consalvo… - PLoS …, 2017 - journals.plos.org
Neuronal migration disorders are a clinically and genetically heterogeneous group of
malformations of cortical development, frequently responsible for severe disability. Despite …

Evaluation of subependymal gray matter heterotopias on fetal MRI

UD Nagaraj, JL Peiro, KS Bierbrauer… - American Journal of …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Subependymal grey matter heterotopias are seen in a
high proportion of children with Chiari II malformation and are potentially clinically relevant …

Stereo‐EEG–based ictal functional connectivity in patients with periventricular nodular heterotopia–related epilepsy

M Zanello, E Garnier, R Carron, A Jegou, S Lagarde… - …, 2024 - Wiley Online Library
Nodular heterotopia (NH)–related drug‐resistant epilepsy is challenging due to the deep
location of the NH and the complexity of the underlying epileptogenic network. Using ictal …