We present a review of the characterization of healthy brain aging using MRI with an
emphasis on morphology, lesions, and quantitative MR parameters. A scope review found …

The amygdala plays a key role in many affective behaviors and psychiatric disorders that
differ between men and women. To test whether human amygdala volume (AV) differs …

Background Microstructural changes in deep gray matter (DGM) nuclei are related to
physiological behavior, cognition, and memory. Therefore, it is critical to study age …

Purpose To study deep gray matter susceptibility in multiple sclerosis (MS) by using
quantitative susceptibility mapping (QSM) and to assess the relationship between …

Age and sex can influence brain iron levels. We studied the influence of these variables on
deep gray matter magnetic susceptibilities. In 183 healthy volunteers (44.7±14.2 years …

Increased brain iron concentration is often reported concurrently with disease development
in multiple sclerosis (MS) and other neurodegenerative diseases. However, it is unclear …

Recent advances in susceptibility MRI have dramatically improved the visualization of deep
gray matter brain regions and the quantification of their magnetic properties in vivo …

Multiple sclerosis (MS) is an immune-mediated disease that targets the myelin sheath of
central nervous system (CNS) neurons leading to axon injury, neuronal death, and …

While numerous studies have used magnetic resonance imaging (MRI) to elucidate
normative age‐related trajectories in subcortical structures across the human lifespan, there …

Background Iron accumulates in brain tissue in healthy subjects during aging. Our goal was
to conduct a detailed analysis of iron deposition patterns in the cerebral deep grey matter …