[HTML][HTML] Current and future trends on diagnosis and prognosis of glioblastoma: from molecular biology to proteomics

AS Silantyev, L Falzone, M Libra, OI Gurina… - Cells, 2019 - mdpi.com
Glioblastoma multiforme is the most aggressive malignant tumor of the central nervous
system. Due to the absence of effective pharmacological and surgical treatments, the …

[HTML][HTML] Updates in IDH-wildtype glioblastoma

JM Melhem, J Detsky, MJ Lim-Fat, JR Perry - Neurotherapeutics, 2022 - Elsevier
Glioblastoma is the most aggressive primary brain tumor with a poor prognosis. The 2021
WHO CNS5 classification has further stressed the importance of molecular signatures in …

[HTML][HTML] Imaging biomarkers for clinical applications in neuro-oncology: current status and future perspectives

FY Chiu, Y Yen - Biomarker Research, 2023 - Springer
Biomarker discovery and development are popular for detecting the subtle diseases.
However, biomarkers are needed to be validated and approved, and even fewer are ever …

[HTML][HTML] Clinical applications of contrast-enhanced perfusion MRI techniques in gliomas: recent advances and current challenges

J Zhang, H Liu, H Tong, S Wang, Y Yang… - Contrast media & …, 2017 - hindawi.com
Gliomas possess complex and heterogeneous vasculatures with abnormal hemodynamics.
Despite considerable advances in diagnostic and therapeutic techniques for improving …

[HTML][HTML] Assessment of glioblastoma response in the era of bevacizumab: longstanding and emergent challenges in the imaging evaluation of pseudoresponse

OD Arevalo, C Soto, P Rabiei, A Kamali… - Frontiers in …, 2019 - frontiersin.org
Glioblastoma is the deadliest primary malignant brain neoplasm, and despite the availability
of many treatment options, its prognosis remains somber. Enhancement detected by …

The significant role of microRNAs in gliomas angiogenesis: a particular focus on molecular mechanisms and opportunities for clinical application

A Mafi, R Mannani, S Khalilollah, N Hedayati… - Cellular and Molecular …, 2023 - Springer
MicroRNAs (miRNAs) are non-coding RNAs with only 20–22 nucleic acids that inhibit gene
transcription and translation by binding to mRNA. MiRNAs have a diverse set of target genes …

Assessment of brain tumors by magnetic resonance dynamic susceptibility contrast perfusion-weighted imaging and computed tomography perfusion: A comparison …

E Scola, I Desideri, A Bianchi, D Gadda, G Busto… - La radiologia …, 2022 - Springer
Purpose To investigate the association and agreement between magnetic resonance
dynamic susceptibility contrast perfusion-weighted imaging (DSC-PWI) and computed …

[HTML][HTML] A radiomics-based comparative study on arterial spin labeling and dynamic susceptibility contrast perfusion-weighted imaging in gliomas

T Hashido, S Saito, T Ishida - Scientific reports, 2020 - nature.com
Radiomics has potential for reflecting the differences in glioma perfusion heterogeneity
between arterial spin labeling (ASL) and dynamic susceptibility contrast (DSC) imaging. The …

[HTML][HTML] Endothelial-tumor cell interaction in brain and CNS malignancies

M Peleli, A Moustakas, A Papapetropoulos - International journal of …, 2020 - mdpi.com
Glioblastoma and other brain or CNS malignancies (like neuroblastoma and
medulloblastoma) are difficult to treat and are characterized by excessive vascularization …

[HTML][HTML] Deep learning based on dynamic susceptibility contrast MR imaging for prediction of local progression in adult-type diffuse glioma (grade 4)

D Heo, J Lee, RE Yoo, SH Choi, TM Kim, CK Park… - Scientific Reports, 2023 - nature.com
Adult-type diffuse glioma (grade 4) has infiltrating nature, and therefore local progression is
likely to occur within surrounding non-enhancing T2 hyperintense areas even after gross …