Thalamic iron differentiates primary-progressive and relapsing-remitting multiple sclerosis

A Burgetova, P Dusek, M Vaneckova… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Potential differences between primary progressive and
relapsing remitting multiple sclerosis are the subject of ongoing controversial discussions …

Iron deposition in the gray matter in patients with relapse-remitting multiple sclerosis: a longitudinal study using three-dimensional (3D)-enhanced T2*-weighted …

S Du, SK Sah, C Zeng, J Wang, Y Liu, H Xiong… - European journal of …, 2015 - Elsevier
Purpose To investigate the relationship between the iron content by magnetic resonance
imaging (MRI) and clinic correlation in patients with relapse-remitting multiple sclerosis …

Unraveling deep gray matter atrophy and iron and myelin changes in multiple sclerosis

G Pontillo, M Petracca, S Monti… - American Journal …, 2021 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Modifications of magnetic susceptibility have been
consistently demonstrated in the subcortical gray matter of MS patients, but some …

Iron deposition in the precentral grey matter in patients with multiple sclerosis: a quantitative study using susceptibility-weighted imaging

R Rumzan, J Wang, C Zeng, X Chen, Y Li, T Luo… - European Journal of …, 2013 - Elsevier
PURPOSE: Several studies suggest that iron deposition may play a role in multiple sclerosis
(MS) pathology. Three-dimensional (3D) enhanced T2*-weighted angiography (ESWAN) at …

Longitudinal MR imaging of iron in multiple sclerosis: an imaging marker of disease

AJ Walsh, G Blevins, RM Lebel, P Seres, DJ Emery… - Radiology, 2014 - pubs.rsna.org
Purpose To investigate the relationship between magnetic resonance (MR) imaging markers
of iron content and disease severity in patients with multiple sclerosis (MS) over a 2-year …

Cognitive implications of deep gray matter iron in multiple sclerosis

E Fujiwara, JA Kmech, D Cobzas… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Deep gray matter iron accumulation is increasingly
recognized in association with multiple sclerosis and can be measured in vivo with MR …

Quantitative assessment of brain iron by R2* relaxometry in patients with clinically isolated syndrome and relapsing–remitting multiple sclerosis

M Khalil, C Enzinger, C Langkammer… - Multiple Sclerosis …, 2009 - journals.sagepub.com
Background Increased iron deposition has been implicated in the pathophysiology of
multiple sclerosis (MS), based on visual analysis of signal reduction on T2-weighted images …

Multiple sclerosis: validation of MR imaging for quantification and detection of iron

AJ Walsh, RM Lebel, A Eissa, G Blevins, I Catz, JQ Lu… - Radiology, 2013 - pubs.rsna.org
Purpose To investigate the relationship between iron staining and magnetic resonance (MR)
imaging measurements in postmortem subjects with multiple sclerosis (MS). Materials and …

Cortical and subcortical morphometric and iron changes in relapsing-remitting multiple sclerosis and their association with white matter T2 lesion load: a 3-tesla …

A Al-Radaideh, I Athamneh, H Alabadi… - Clinical …, 2019 - Springer
Introduction This study was carried out to investigate the global and regional morphometric
and iron changes in grey matter (GM) of multiple sclerosis (MS) patients and link them to the …

[HTML][HTML] Iron deposition in multiple sclerosis: overall load or distribution alteration?

E Hamdy, AA Galeel, I Ramadan, D Gaber… - European Radiology …, 2022 - Springer
Background Though abnormal iron deposition has been reported in specific brain regions in
multiple sclerosis (MS), no data exist about whether the overall quantity of iron in the brain is …